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是 no talk 还是no talking

no 是形容词,形容词接名词所以talk动词要变成名词形式,也就是talking,而not是副词可以直接修饰动词,所以talk不要变形。

买了个TALKING/SNOOZE电子表不知道怎么调试

先按MODE之后长按HOUR屏幕上会出现on或of点HOUR调到on就可以调整时间啦。

iftwo men stand close to each other while talking,they cannot be from是什么意思

from 后面应该填写Britain

talking to和talking for 有什么区别??

for prep. 介词时(表示目的)为了, 因为, 至于, 对于, 适合于 例句:I will wait for you.conj. 连词时因为 例句:Einstein received worldwide praise for his scientific research.to prep. 介词to的用法 一:表示相对,针对 be strange to 二:表示对比,比较 1:以-ior结尾的形容词,后接介词to表示比较 senior,junior 2: 一些本身就含有比较或比拟意思的形容词 A is similar to B in many ways. 3:表示一些先后顺序的形容词 they returned to their hometown 4: to也偶尔出现在个别动词之后,与动词形成固定词组,表示比较 compare to sth. 5: to与及个别的名词构成比较之意, Going to an under water concert is a great alternative to going to dinner. 三: 表示修饰关系 1: 表示回复,反应意思的词 answer to question 2: 表示建筑构件的词汇 the approach to science 3: 表示人物职位和官衔的词 assistant to manager 4: 表示权利和许可的词汇 Everyone has an equal right to 5: 表示栅栏或障碍的词汇 the barrier to progress 6: 表示与书籍,文本相关的词 introduction to passage 7: 表示恭喜或是祝贺 Let"s drink to Dick"s success in business 8: 另外还有一些名词符合这种用法,有的具有两者息息相关,缺一不可的含义 guide to action 四: to还具有依据,伴随,和着节奏的含义 sing to piano (一):表示相关联,相连接 be related to (二):表示反对和赞同 1:to引导的表示反对,抗拒,对抗意义的词组 Be opposed to 2: to引导的表示同意,赞同意义的词组 The employer consented to give him a salary raise 3: 表示投降,屈服,服从的含义 confess to 五: 表示趋势或倾向, tend to 六: 表示对事情的坚持与执着 He still holds on to his original views 七: 表示约束,局限 limit to 八: 表示一种习惯或是一种适应性 get (be) to 九: 表示起因和原由 due to 十: 表示目的或结果 lead to of prep. 介词...的, 由...制成的, 离, 关于, 对于用法 1: 表示剥夺,除去 clarify the river of flowing rubbish 2: of接直接宾语 remind sb. of his duties 3: of接间接宾语 ask a question of sb 4: of表示人物的特性,籍贯,特性或出生等 He is of Irish descend 5: 固定词组 The room smells of stale cabbage. http://zhidao.baidu.com/question/8520886.html供您参考

谁知道you are talking的意思?

你这么说才合我意呢~~

不要讲话是no talking 还是not talking

notalking的本身意思是禁止说话

不要讲话是no talking 还是not talking?

不要讲话是no talking 还是not talking祈使句用 No + 动名词 或者说 No +动名词构成否定祈使句例如: No parking here (这里不能停车/ 禁止停车 )不要讲话,属于祈使句,因此需要用No talking 祈使句否定另外一种 Don"t +动词原形Do not leave your seat until the plane is airborne. 机升空时不要离开座位。 Don"t talk in class 不要在课堂上讲话not +非谓语动词 (用作句子的状语)Not wishing to antagonize her further, he said no more. 他不愿惹她更生气,便不再说话。 The teacher asked us not to be late for school这个老师要我们不要上学迟到.not +谓语动词 He"s not very good at arithmetic. 他不太擅长算术。He didn"t always win the arguments, but he often was right... 他并非在争辩中总是能赢,但他经常是对的。Eva was adamant that she would not come. 伊娃坚决不来。

talking to是什么意思

说话,望采纳

a talking robot为什么用talking

talking robot说话机器人,这是一个短语,talking在这里是动名词形式,用以修饰robot

for all my talking是啥意思

for all my talking 全部释义和例句>>我所有的谈话talking 英["tu0254:ku026au014b] 美["tu0254:ku026au014b] n. 讲话; (表示对所说的事情感兴趣) 你这话说着了; 提起; 说到; adj. 会说话的; 讲话的; 饶舌的; 富于表情的; v. 说话; 讨论; 说( talk的现在分词 ); (用以强调款额、情况严重程度等) 讲的是; [例句]That"s my wife you were talking to.刚才和你说话的人是我老婆。

talking quietly和talk quiet

A 考查固定搭配。Stop to do sth.停下来开始做另一件事;stop doing sth.停止做某事;根据句意,应是老师来了。请停止讲话,保持安静。所以第一空用talking;keep后跟形容词,表示保持某种状态。所以选A。

Keep Talking 歌词

歌曲名:Keep Talking歌手:Pink Floyd专辑:PulsePink Floyd: Keep TalkingFor millions of years mankind lived just like the animalsThen something happenend which unleashed the power of our imaginationWe learned to talkThere"s a silence surrounding meI can"t seem to think straightI"ll sit in the cornerNo one can bother meI think I should speak now. (Why won"t you talk to me?)I can"t seem to speak now. (You never talk to me.)My words won"t come out right. (What are you thinking?)I feel like I"m drowning. (What are you feeling?)I"m feeling weak now. (What are you thinking?)But I can"t show my weakness. (You never talk to me.)I sometimes wonder, (What are you feeling?)Where do we go from here? (What are you feeling?)It doesn"t have to be like thisAll we need to do is make sure we keep talkingWhy won"t you talk to me? (I feel like I"m drowning.)You never talk to me. (You know I can"t breathe now.)What are you thinking? (We"re going nowhere.)What are you feeling? (We"re going nowhere.)Why won"t you talk to meYou never talk to meWhat are you thinkingWhere do we go from hereIt doesn"t have to be like thisAll we need to do is make sure we keep talkinghttp://music.baidu.com/song/8323796

闹钟上的talking/snooze是什么意思

报时/贪睡 键

talk的用法和固定搭配 以及同义单词用法总结

1、talk 意为“交谈,谈话,侧重两者之间相互说话。固定搭配形式有: talk to /with sb. 和某人交谈;talk about sth. 谈论某事;She is talking with Lucy in English.她正在和露茜用英语交谈;What are you talking about?你们在谈论什么;The teacher is talking to him.老师正在和他谈话。 2、speak 强调说的方式和能力 。可后接语言作宾语。固定搭配形式有: speak English讲英语; speak to sb. 跟某人说话;speak highly of 高度赞扬。 3、tell 表示“讲述,告诉“,可接双宾语。固定搭配形式有:tell sb. sth. 告诉某人某事;tell sth. to sb. 对某人说某事;tell sb. (not) to do sth. 告诉某人(不要)做某事;tell a story 讲故事。 4、say 表示”说话“,侧重说话的内容,宾语可以是名词,代词或从句。固定搭配形式有:say to sb. 对某人说;say thanks/sorry to sb. 向某人感谢/道歉;say yes/no to sb. 同意/拒绝某人。

but i think 后为什么要加talking?

But I think后面如果接了宾语从句或宾语的话。动词作宾语就要加上ing。是它起名词的作用。给你举一个例子。 I think talking is very interesting.在这里talking必须使用动名词。因为他在这里做了宾语。

who were you talking to at the party?为什么要用talking?

weretalkingwere是are的过去时BEDOINGSTH是现在进行时,所以动词要加ing

talking about、talking to和talking with的区别及用法

答:talk是“谈”,about是“关于”,to是‘对着",with是‘和...一起", 所以talk about 相当于汉语的“谈论”,宾语可以是事情,与可以是人, talk to是“对...谈话”,宾语是人,常为上级对下级. talk with是“和..交谈”,宾语是人,同辈,或当同辈来看.

talking的原型是什么

talk [英][tu0254:k][美][tu0254k]v.说话; 讨论; 讲,说; 说闲话; n.交谈; 讨论; 报告; 空话

to talk=talking吗

简单点给你说吧:to talk是要说什么,talking是现在在说什么

talking about,talking to和talking with的区别及用法

talking about就是说 讲述/谈论某些事情 譬如 Mike and Jane are talking about their frist trip to China next month.Mike 还有 Jane 在谈论他们下个月的第一次中国之旅。Talking to就是向某人说话啊譬如 I talked to him about my French course yesterday.我昨天和他说了关于我法语课程的事情Talking with 就是和谁说话啊 Mr.Row is talking with his boss.Row和他老板正在聊天.

talking造句四年级上

1.Football fans have been talking up the match. 球迷们一直在热烈讨论那场球赛。2.The teacher came down on her for talking in class. 老师因为她在上课时说话而严厉申斥她。3.While I was talking with her, she sprawled her legs in the sofa. 我与她闲谈时,她叉开腿懒散地躺在沙发上。

talking about、talking to和talking with的区别及用法

答:talk是“谈”,about是“关于”,to是‘对着",with是‘和...一起", 所以talk about 相当于汉语的“谈论”,宾语可以是事情,与可以是人, talk to是“对...谈话”,宾语是人,常为上级对下级. talk with是“和..交谈”,宾语是人,同辈,或当同辈来看.

talking造句四年级上

1.Football fans have been talking up the match. 球迷们一直在热烈讨论那场球赛。2.The teacher came down on her for talking in class. 老师因为她在上课时说话而严厉申斥她。3.While I was talking with her, she sprawled her legs in the sofa. 我与她闲谈时,她叉开腿懒散地躺在沙发上。

talking about什么意思

talking about表示谈论,about后面跟的是谈论的内容,如We are talking about the weather.我们正在谈论天气。

梁心颐的《Talking》 歌词

Talking演唱:梁心颐又坐在著看你的嘴巴运动它非常有把握但仔细听其实我听不太懂因为我怀疑你逻辑有点漏洞Oh yeah 我怀疑你很久你做什麼都有一百个理由没做你又能有一百个藉口我想说快一点 快一点难道真的要我戳破?Oh no 我想你一直都在talking 太多http://music.baidu.com/song/30333689

talking造句 talkingの例文 "talking"是什麼意思

I would pke to talk to the manager himself . 我要和经理本人谈一谈。 Talking is one thing , doing is another . 说是一回事,做又是一回事。 You talk as if there were dangers . 你讲话好像有什么要大祸临头似的。 My will to talk to him gradually died . 我和他谈话的愿望逐渐消失了。 After the talk , he began to thaw . 谈话之后,他的态度开始缓和下来。 I have an hour "s talk in store for you . 我有一个钟头的话要跟你谈。 What kind of double talk was this ? 这是一种什么样的模棱两可的话呢? That"s the silly talk of scholarly people . 那是有学问的人说的傻话。 His promises were just so much meaningless talk . 他许诺的都是空话。 The reddleman suddenly ceased to talk idly . 红土贩子忽然停止了闲谈。 It"s difficult to see talking in a sentence. 用 talking 造句挺难的 A great deal of the talk was about oil . 谈话大多集中在石油问题上。 He is always ready to talk at length . 他一有机会就长篇大论讲个没完。 He"s talked with some of our research people . 他对那些研究人员说了。 All this talk seemed to me so futile . 所有这些谈话在我看来全都白费。 I know him by sight , but not to talk to . 我见过他,但没跟他说过话。 She outpned the main points of the talk . 她作了那次讲话内容的提要。 Why do you talk to me of ing together ? 为什么同我谈起合伙来了? They finally managed to talk her round . 他们最后终于设法说服了她。 Stanley pierce spits when he talks . 斯坦利庇亚斯讲话时唾沫纷飞。 He can talk people over to his own views . 他能说服别人听从他的意见。 Who was that man you were talking to ? 刚才你正和一个人说话,他是谁? She went on, talking somewhat at random . 她继续说下去,有些语无论次。 He talked of his adventure all day long . 他终日不停地谈他的奇遇。 Both of them were talking more freely . 他们两个谈起话来都比较自在了。 Let "s talk it over again some other time . 我们另外找时间再谈吧。 We talked until midnight and then separated . 我们一直谈到深夜才分手。 I "ve got something to talk over with you . 我有个事儿跟大家念叨念叨。 He immediately began to talk to drummle . 他立即和珠穆尔攀谈起来。 Do n"t talk about others behind their backs . 不要在背后议论别人。 I"m glad to hear him talking straight . 我高兴听到他直截了当地说话了。 It"s difficult to see talking in a sentence. 用 talking 造句挺难的 A few men were talking among themselves . 有几个人正自顾自在聊天。 Why do you butt in when grown people are talking ? 大人说话你插什么嘴? She wished she could talk things out with him .. 她希望能与他详谈一次。 The more they talked , the more they disagreed ... 两人越说越拧。 But you haven"t talked to my hu *** and . 不过,你还没有跟我先生讲过话呐。 I have done talking -- it is time to act . 我话已说完该采取行动了。 Then there was talk of peace and a position . 随后又有休战媾和之说。 I switch off when he starts talking about cars . 他一谈起汽车我就厌烦。 We can talk more fortably there . 我们在那里可以谈得更畅快些。 Come and talk to me when you have the chance . 有工夫来找我聊聊。 One day , i had a long talk with him . 一天,我和他作了一次长谈。 From then on he refused to talk about it . 从那以后他就不再谈这件事了。 The talks proceeded in a friendly atmosphere . 会谈在友好的气氛中进行。 The talk turned on the advantages of measles . 话题转到了出麻疹的好处。 He talked a great deal and rapidly . 他说起话来滔滔不绝,而且速度很快。 He won"t talk straight from the shoulder . 他说话从来不直截了当。 Pay attention when i am talking to you ! 我跟你说话的时候,你要留心听。 It requires a lot of talking to convince him . 要说服他很费口舌。 My love of talk still abides with me . 我还保持著喜欢谈天的习惯。 Now don"t talk stuff before aunt polly . 快别在波莉姑姑面前说这些废话。 It"s difficult to see talking in a sentence. 用 talking 造句挺难的

talk和talking两者用法与意义有什么区别,

talk vt.说;谈话;讨论 vi.谈话;说闲话 n.谈话;演讲;空谈 talking adj.说话的,多嘴的;有表情的 n.讲话,谈论 v.谈论;讲话(talk的ing形式) talk是及物动词(vt.) 后面要跟宾语 talking 是不及物动词(vi.) 不跟宾语.

talking是什么意思?

talking是.形容词1.说话的2.有表情的3.饶舌的,多嘴的n名词.1.讲话;谈话;讨论也可以是talk的动词ing形式原型是talk

talking是什么意思

  talking英 ["tu0254:ku026au014b] 美 ["tu0254:ku026au014b]  n.讲话; (表示对所说的事情感兴趣) 你这话说着了; 提起; 说到;  adj.会说话的; 讲话的; 饶舌的; 富于表情的;  v.说话; 讨论; 说; ( talk的现在分词 ) (用以强调款额、情况严重程度等) 讲的是;  [网络]谈话; 交谈; 五月天;  [例句]When he was talking to a girl he could hardly speak, and when he did speak he talked gibberish.  他跟女孩儿讲话时几乎张不了口,即便张了口,说起话来也词不达意。  [其他]形近词: hulking walking talkies

talking怎么读

talking [u02c8tu0254u02d0ku026au014b] v. 说话; 讲话; 谈话; 讨论,谈论,商谈,洽谈(通常指重大的事); (用某种语言) 讲,说; [词典] talk的现在分词; [例句]That"s my wife you were talking to刚才和你说话的人是我老婆。[其他] 原型: talk

talking的英文是什么意思

交谈

talking中文是什么意思

中文意思:谈话

it was nice talking to you为什么用 talking而不用to talk

这里的talking应该表示 谈话已经结束,是谈话结束时的用语. ing形式可用于表示 动作已结束. to do 表示事情还未发生. 就像我们常说的 forget doing 和forget to do 的区别一样. 另一方面,nice to meet you 和nice meeting you,前者表示很高兴见到你;而后者表示要再见了,说明已结束.

talk的过去式是什么

talk的过去式是:talked。talk的例句是用作动词(v.)I wish to talk with you in private.我希望能私下里同你谈话。talk的意思是v.交谈;商讨;演讲;阐述;劝服;n.谈话;会谈;讨论;讲话;空谈。一、详尽释义v.(动词)商谈,讨论,商讨唠叨,饶舌谈论,谈话,讲,说,谈,说话,交谈说闲话演讲揭人隐私表达思想,表示意思招供劝说谈着消磨(光阴)讲着话使...通信空谈嚷叫,发响攀谈,搭腔,高谈阔论,聊聊,胡扯洽谈n.(名词)话题谈判谈话,交谈空话,空谈方言演讲,讲演流言蜚语,谣言,谣传会谈隐语特定说话方式行话闲话讨论,商谈,商议二、词典解释1.讲话;说话When youtalk, you use spoken language to express your thoughts, ideas, or feelings.e.g. He was too distressed totalk...他伤心得讲不出话来。e.g. A teacher reprimanded a girl for talking in class...老师斥责了一个在课堂上说话的女生。2.交谈;谈话If youtalk to someone, you have a conversation with them. You can also say that two peopletalk .e.g. We talked and laughed a great deal...我们说笑了很久。e.g. I talked to him yesterday...昨天我和他谈过了。3.谈心,倾诉,诉说心事If youtalk to someone, you tell them about the things that are worrying you. You can also say that two peopletalk .e.g. Your first step should be totalk to a teacher or school counselor...你第一步应该是去找老师或学校辅导员谈谈。e.g. There"s no one she cantalk to, and she"s on the verge of collapse...她找不到一个可以倾诉的对象,快要崩溃了。4.发表谈话;发表观点If youtalk on orabout something, you make an informal speech telling people what you know or think about it.e.g. She willtalk on the issues she cares passionately about including education and nursery care...她将会谈一些自己十分感兴趣的话题,包括教育和幼儿护理。e.g. He intends totalk to young people about the dangers of AIDS.他打算和青年人谈谈艾滋病的危害。There are some differences in the way the verbsspeak andtalk are used. When youspeak, you could, for example, be addressing someone or making a speech.Talk is more likely to be used when you are referring to a conversation or discussion.I talked about it with my family at dinner... Sometimes we"d talk all night.Talk can also be used to emphasize the activity of saying things, rather than the words that are spoken.She thought I talked too much. See also note atdiscuss.speak 和 talk 两个动词的用法有些不同。speak 可以表示对人讲话或发表演讲,而 talk 更有可能表示谈话或讨论:I talked about it with my family at dinner (吃晚饭时,我和家人讨论了这件事),Sometimes we"d talk all night (有时我们能谈上一宿)。talk 也可以用来强调说话的行为,而非所说的话,例如:She thought I talked too much (她嫌我话太多)。参见 discuss 词条下的说明。5.(通常指国家、劳资间为达成某种协定的)谈判,商谈Talks are formal discussions intended to produce an agreement, usually between different countries or between employers and employees.e.g. ...the next round of Middle East peace talks...下一轮中东和平谈判e.g. Talks between striking railway workers and the Polish government have broken down...罢工的铁路工人和波兰政府间举行的谈判已经破裂了。6.磋商;讨论If one group of peopletalks to another, or if two groupstalk, they have formal discussions in order to do a deal or produce an agreement.e.g. We"re talking to some people about opening an office in London...我们在和一些人讨论在伦敦设立办事处的事儿。e.g. The company talked with many potential investors...公司和许多潜在的投资人举行了磋商。7.会谈;对话;谈判When different countries or different sides in a disputetalk, ortalk to each other, they discuss their differences in order to try and settle the dispute.talk的意思e.g. The Foreign Minister said he was ready totalk to any country that had no hostile intentions...外交部长说他愿意和任何不怀敌意的国家举行会谈。e.g. They are collecting information in preparation for the day when the two sides sit down andtalk...他们正在收集情报,为双方坐下来谈判的那一天做准备。8.议论;嚼舌;说闲话If peopleare talking about another person orare talking, they are discussing that person.e.g. Everyone is talking about him...人人都在议论他。e.g. People willtalk, but you have to get on with your life.人们会有议论,但日子还得过下去。9.(通常指不情愿地)供出,招认,招供If someonetalks when they are being held by police or soldiers, they reveal important or secret information, usually unwillingly.e.g. They"lltalk, they"ll implicate me.他们会招供的,他们会把我牵连进去的。10.讲,说,操(某种语言或口音)If youtalk a particular language ortalk with a particular accent, you use that language or have that accent when you speak.talk的解释e.g. You don"t sound like a foreigner talking English...听你讲英语,不像是外国人。e.g. They were amazed that I was talking in an Irish accent.我说话带爱尔兰口音让他们感到很惊奇。11.谈论,讨论(政治、体育等)If youtalk something such as politics or sport, you discuss it.talk是什么意思e.g. The guests were mostly middle-aged men talking business.顾客多数是些谈正事的中年男子。12.说,讲(?的话)You can usetalk to say what you think of the ideas that someone is expressing. For example, if you say that someoneis talking sense, you mean that you think the opinions they are expressing are sensible.e.g. You must admit George, you"re talking absolute rubbish.乔治,你得承认你说的全都是废话。13.谈论;讨论You can say that youare talking a particular thing to draw attention to your topic or to point out a characteristic of what you are discussing.e.g. We"re nottalking a murder here; we"retalking poker machines or gambling — things that are misdemeanors in most states...我们现在讨论的不是谋杀,而是扑克机或赌博——这些在多数州只能算轻罪了。e.g. We"re talking megabucks this time.我们这次谈的可是上百万的买卖。14.(想法、威胁)说说而已,空谈If you say that something such as an idea or threat is justtalk, orall talk, you mean that it does not mean or matter much, because people are exaggerating about it or do not really intend to do anything about it.e.g. Has much of this actually been tried here? Or is it justtalk?...这个多半已经真正尝试过了吗?还是仅仅说说而已?e.g. Conditions should be laid down. Otherwise it"s alltalk.应该先定下条件,否则全是空谈。15.这才叫?;真是You can saytalk about before mentioning a particular expression or situation, when you mean that something is a very striking or clear example of that expression or situation.e.g. Took us quite a while to get here, didn"t it?Talk about Fate moving in a mysterious way!...我们用了很长时间才走到今天这步,是吧?这就叫命运难测啊!e.g. She threw the cake I"d made on the floor and stood on it.Talk about being humiliated!她把我做的蛋糕扔到地上,然后踩在了上面。真是欺人太甚!16.我说,说到,谈到(用于引出新话题)You can use the expressiontalking of to introduce a new topic that you want to discuss, and to link it to something that has already been mentioned.talk是什么意思e.g. Belvoir Farms produce a delicious elderflower tea. Talking of elderflower, you might wish to try Elderflower Champagne.贝尔沃农场生产一种非常好喝的接骨木花茶。说到接骨木花,你兴许想尝尝接骨木花香槟酒。e.g. As it says in the Bible, my cup is running over. Talking of which, I must get you a cup of tea.正如《圣经》所说,给我恩赐太多了,我的杯子已经满满当当了。说到杯子,我得去给你倒杯茶来。17. totalk shop -> see shop相关词组:talk aroundtalk backtalk downtalk down totalk intotalk outtalk out oftalk overtalk roundtalk throughtalk up三、网络解释1. 交谈:在和<>(talk)杂志(现已不再出版)的保守派记者塔克.卡尔森的对话中,据卡尔森说,布什曾经模仿卡拉.法耶.塔克在有线新闻电视网(cnn)中接受拉里.金的采访时好像在祈求赦免的样子.四、例句I wish to talk with you in private.我希望能私下里同你谈话。We need to hold another meeting next week to talk about some technical problems.我们需要在下周再举行一次会议,来讨论一些技术性的问题。In the hall a woman was talking on diet and health.在那个大厅里,一名女性正在就饮食与健康发表演讲。He went on to talk about the world situation at present.他接着又阐述了当期的世界形势。He talked his father into lending him the car.他说服他的父亲把汽车借给他。I had a long talk with her that night.那天晚上,我和她秉烛长谈。The talks between the two premiers will be held next month.两国总理的会谈将于下月举行。The officers held a long talk about the price control and pay rise.官员们就价格调控和工资上涨进行了长时间的讨论。She delivered a talk on philosophy to the society.她给学会作了一次有关哲学的讲话。In politics there is too much talk and not enough action.在政治方面向来是说得多做得少。五、常见句型用作动词(v.)用作不及物动词S+~(+A)They were talking with each other.他们正在交谈。They talked loudly.他们大声谈话。Talk much, and err much.言多必失。They were all talking at once.他们一下子全都说起话来。He could have come to the office if he wanted to talk.他若想商谈什么事情,本可以到办公室来。Human beings can talk; animals can"t.人能讲话,动物不能。Some parrots can talk.有些鹦鹉能学人讲话。People who cannot speak or hear can talk by using sign language.不能讲话或听不见的人可以用手语交谈。Many deaf-mutes began to talk after acupuncture treatment.许多聋哑人经过针刺治疗开始能说话了。We must stop meeting like this—people are beginning to talk!我们绝不能再这样约会了——人们已经说起闲话来了!Don"t park your car outside my house; you know how people talk!别把你的车停在我的屋子外面,你知道人家会说些什么!The police persuaded the suspect to talk.警方劝嫌疑犯招供。用作系动词S+~+ adj.He likes to talk big as though he was an important person.他老爱说大话,就仿佛他是一位要人似的。You can"t believe more than half of what he says; he always likes to talk big.他说的话你最多只能信一半,他总喜欢说大话。She talked quite sensible.她说得很有道理。用作及物动词S+~+ n./pron.Please talk sense.请谈些有意义的话。You"re talking nonsense!你真是胡说八道。Don"t talk nonsense! I refuse to listen.别胡扯了,我不愿听!He would never do such a thing. You"re talking rubbish! Rubbish!他决不会干这样的事。你瞎说!瞎说!The man doesn"t talk reason.这个人不讲道理。I talk Chinese.我讲汉语。They kept on talking philosophy throughout the night.他们通宵都在谈论哲学。The instructor never talks personalities.那位导师从不飞短流长说人坏话。1The day"s news is being talked.人们正在谈论今天的新闻。用作宾补动词S+~+ n./pron. + adj.They talk themselves ill.他们讲得都病倒了。S+~+ n./pron. + prep. -phraseHe talked me to death.他说得我无地自容。用作名词(n.)His talk was so diffuse that I missed his point.他的谈话漫无边际,我抓不住他的要点。The dean has arranged with me about a talk in the evening.系主任已约定晚上与我谈话。He hospitably asked me to step in and have a talk.他殷勤地邀请我进去谈谈。It will afford us great pleasure to have a business talk with you.和你共谈业务将给我们带来无限喜悦。I have a very sharp recollection of my last talk with him two years ago.两年前我和他最后一次谈话的情景仍历历在目。There was a delay before the car came to collect us so we made small talk in the meantime.汽车来接我们晚了,因此在此期间我们便聊开了。He used so many technical terms in his talk that the audience could not make head or tail of it.他在讲话中用了许多专门术语,听众简直摸不着头脑。I went to his talk with great interest, but to my disappointment, nothing very new came forth.我抱着极大的兴趣去听他的讲话,但使我失望的是讲话中没有什么新东西。I blushed at my friend"s bad manners and loud talk.我为我朋友的不礼貌和高声说话而感

一句话中talk是在最前面:talking topeople 请问talking为什么加上ing?

Talking 放于句首,是动名词结构作主语的一种用法。

have a talk正确还是have a talking正确

Let"s have a talk. 不用想语法那些问题,这个固定用语,记住就好

talking谐音怎么读

互 督由 sing克 又啊 套克因吐(这个think实在是找不到合适的中文来谐音 还有“套克因”尽量读快一点,连读,空格表示短暂的停顿)希望对你有帮助

talkinng后面要要加to吗?

那你的这个的话肯定是要加建一个吐的当然了如果是和别人的话用建议还是加为仁和一是一些

talk的过去式是什么

drink-drankam/is-wasdo-didgo-wentsee-sawhave-hadsleep-sleptread-readclean-cleanedplay-playedtalk-talkedwatch-watchedwash-washedstay-stayed这些是我老师经常靠我们的

talk和talking的用法区别,高手来支招...!!!!!!!!

介词后得跟动名词,而某些动词后与可跟动名词,表示"当时的动作"

taling与talking的区别

taling这个单词是没有的,你是不是想问telling?telling的话,和talking一样都是动词的现在分词形式,不过前者强调说话的内容,搭配一般是tellsbsth,而后者强调说话的动作,一般是talkto/withsb。如果是talk和talking的区别的话就更简单了,后者是正在说,现在进行时;前者则是普通形式,一般现在时

演唱会talk还是talking环节

talking环节。演唱会是指在观众前的现场表演,通常是音乐的表演。演唱会是talking环节,不是talk,talking是可以邀请一个幸运儿与明星进行交谈,该环节明星分享了心声,可以吸引了大量人群的关注。

talking 与chatting的区别?

talking说话chatting聊天聊天 [ liáo tiān ] 生词本基本释义 详细释义 [ liáo tiān ]以轻松随便的方式谈话,不拘礼仪地,不受拘束地谈话。

was talking , has been talking , has talked ,talke 这四个的区别和意思

wastalking表示在过去的某个时间里正在谈话hasbeentalking表示谈话这个动作从过去发生到现在仍在进行,并且可能延续到将来hastalked表示从过去到现在已经谈过了talked表示过去谈话这一动作

talking后面接什么?

关系从句或者定语从句定语从句(attributive clause)也叫形容词性从句(adjective clause)或 关系从句 ( relative clause ),是一种由关系词引导的从句形式的后置修饰语.例The man whom is talking with my teacher is John"s father.和我老师说话的那个男人是约翰的爸爸。希望可以帮到您。

speaking和talking

speak强调说的动作,不强调所说的内容 .作及物动词时,常以某种 语言作宾语.作不及物动词时,常见的搭配形式有:speak of something/somebody谈到某事(某人)speak to sb 跟某 人讲话,此外speak还可用于在较为正式的场合了表演讲或演说.Can you speak Japanese?你会说日语吗?She is speaking to her teacher.她正在跟她的老师说话.He spoke at the meeting yesterday.他昨天在会上讲了话.▲ talk 一般为不及物动词,意思是“交谈,谈话,着重强调两具之间的 相互说话.eg:She is talking with Lucy in English.她正在和露茜用英语交谈.What are you talking about?你们在谈论什么?The teacher is talking to him.老师正在和他谈话.

五月天麦迪逊花园的《talking》是什么意思?

五月天麦迪逊花园的《talking》,是没有任何解释或者歉意,只是暗示自己好委屈被误会。粉丝们买账了,事情过去了,这就是这段talking的意思。玛莎反服贸是石锤的,处处是证据。如果知错了,你倒是道歉啊,如果是犯糊涂了,你倒是解释啊,都没有!没有任何解释或者歉意,只是暗示自己好委屈被误会。粉丝们买账了,事情过去了,这就是这段talking的意思,怕惹祸上身表演的一出戏码。官方对模棱两可的艺人其实是包容的,但是粉丝们自己心里还是要有数,自己的原则、尊严、文化认同先搞清楚,明确自己的底线在哪里,哪些不可以妥协,哪些可以模糊,在尊重自己的基础上再来看待这些偶像们,值不值得你喜欢,配不配让你喜欢。

talk和talking两者用法与意义有什么区别,详细点。谢谢

一个为动词一个为动名词本质区别就是这个

talking怎么读

Iamtalking中的i的发音是大嘴音{ai},发音时气流在嘴巴里绕一圈,叫爱的大嘴音,把“爱”托长读即可am的发音方式是:前面a的发音下巴尽量往下咧,与地面成九十度,气流从口中两侧挤下去,m是闭口应答音talking的发音是:t是爆破音,发音时舌头靠在上齿龈,是轻音,而al的发音是嘴巴成圆形,舌尖触及下齿,振动声带,气流从口中流出,有口腔后部发音,ing发音是舌头先放在下齿龈然后再撒娇即可整个句子用汉语来读的话就是:爱爱目掏克英

what is the song talking about是什么意思?

what is the song talking about翻译成中文就是:这首歌唱的是什么内容。

talking about、talking to和talking with的区别及用法

答:talk是“谈”,about是“关于”,to是‘对着",with是‘和...一起", 所以talk about 相当于汉语的“谈论”,宾语可以是事情,与可以是人, talk to是“对...谈话”,宾语是人,常为上级对下级. talk with是“和..交谈”,宾语是人,同辈,或当同辈来看.

梁静茹 talking 歌词

talking 不是梁静茹讲的一段话么 后面接着talking是静茹唱的《掌声响起》

翻译;talking

谈话 交谈

talking是什么意思?

talking怎么读音

英 [u02c8tu0254u02d0ku026au014b]美 [u02c8tu0254u02d0ku026au014b]说话原型talktalk+ing现在,正在说话。

Are you talking to your mother 里的talking是什么词?

现在分词,Be + talking

talking怎么读

talking的英式读法为[u02c8tu0254u02d0ku026au014b],美式读法为[u02c8tu0254u02d0ku026au014b]。talking作名词时意为交谈、演讲、讨论;作形容此时意为正在谈话的;会学人语的;富于表情的。短语搭配:talking point,话题,论题;talking head,发言人特写头像;talking shop,只会清谈的一群人,清谈馆;talking book,有声读物。双语例句:1、He used the prospect of freedom as bait to trap him into talking.他用自由的前景作诱饵使他开口。2、I had been a little too copious in talking of my country.在谈到自己国家时,我有点太滔滔不绝了。3、As a matter of fact,I was talking to him this afternoon.事实上,我今天下午还在同他谈话。4、We are not talking about subtle errors of judgement,but major fumbles.我们不是在讲判断上的微小错误,而是大错。5、Talking of cards,you"d better take a couple of my business cards.谈到名片的问题,你最好拿两张我的商业名片。

talking怎么读英语

talking的读音为:["tu0254u02d0ku026au014b]。一、talking的翻译1、形容词说话的;多嘴的;富于表情的。2、“talk”的现在分词,谈论,讲话。二、talking例句1、She cast her eyes down modestly while Jack was talking about her.杰克谈及她时她稍稍垂下目光。2、Nothing displeases me more than loud talking.没有比大声谈话更使我不高兴的了。3、Fred left off talking about the firm.弗雷德不再谈论那个公司了。4、We were talking when he leaped in.我们正在谈话, 他跳了进来。5、I can"t endure talking to those scoundrels.与那些无赖们交谈,我真受不了。6、The salesman has a persuasive way of talking.那推销员有一种能说服人的谈话方式。7、While we were talking, a bloke came up.我们正在谈话, 一个人走了过来。

more often中的more能放在often后面吗?且talk more about中的mor

不能,more othen是一个固定短语

俄私人太空公司Success Rockets计划在2024年将Stalker轻型火箭送入近地轨道

据塔斯社4月11日报道, 俄罗斯私人太空公司Success Rockets推出了 Stalker 轻型火箭,计划于 2024 年进入轨道。 据悉,Stalker 火箭旨在将各种格式的卫星(从立方体卫星到微型卫星)发射到近地轨道。该火箭能够将 700 公斤的有效载荷发射到高达 700 公里的轨道上。Success Rockets 首席执行官 Oleg Mansurov 表示,有效载荷质量的计算考虑了太空服务市场的发展前景。他说:“火箭的有效载荷质量是由 SR 团队计算的,同时考虑了专业界对未来 5-10 年航天发射市场发展的预测。” 该公司还计划自行生产用于整流罩和部分火箭主体的碳复合材料。 此前,Mansurov称,Success Rockets在2022年计划启动高度超过100公里的亚轨道火箭,2024年将进行全面轨道发射。 (编译:刘双)

talk about past events 英语作文

China announced Thursday huge tariffs on fertilizer exports and said agricultural land was in rapid decline due to industrialization.China"s official communist news agency Xinhua News announced that export tariffs on fertilizer would increase by 100%. This will cause a virtual shutdown in the export of fertilizer from China. This is necessary to preserve fertilizer for suffering Chinese agriculture.The fertilizer is widely used in rice, corn and wheat growing which is essential to feed the 1.3 billion Chinese. China also hopes to control rapidly rising domestic agricultural costs and inflation."Agricultural costs [in China] are going through the roof. Land prices, the cost of money, the relative cost of labor, fertilizer, a shortage of seeds," said Paul Schulte, of Lehman Brothers in Hong Kong. "Yet rising agricultural prices can be a windfall for those with economies of scale."The China News agency also said the amount of farmland has decreased to crisis levels.Western observers said the two announcements on the same day are an effort to prepare the world for a food shortage crisis in China.故事:Food shortage occurs when food supplies within a bounded region do not provide the energy and nutrients needed by that region"s population. Food shortage is most easily conceptualized as a production problem - not enough food is grown to meet regional needs - but constraints on importation as well as storage can also cause or contribute to food shortage. Food shortage is also created where food is exported from areas where production is adequate or even abundant. Historically, the great hunger of Ireland (1845-1847) and the famine of Bengal (1944) have been attributed more to British political decisions to export locally produced grain supplies without compensating imports than to production shortfalls per se (Woodham-Smith 1962; Sen 1981).Even when production shortfall is the primary cause of insufficient supply, the ecological and political reasons for production problems vary widely. They range from natural disasters such as drought, flood, or fungus, to political disasters such as civil conflict, to misguided economic policies such as price controls- all of which discourage production of essential foods.In all situations of food shortage, many within the region"s population are hungry; but in every food-short region, others still enjoy adequate access to food. Equally, although many are food secure in areas of adequate food production, some still go hungry. These variable patterns of hunger result not only from skewed food distribution within regions based on differential political and economic resources, but also from selective marketing, and from non-market political policies of food extraction or assistance.。。。。。。。。。。。。

she talked too much yesterday and didnt drink enough water she has a very sore throat now翻译

你好!she talked too much yesterday and didnt drink enough water she has a very sore throat now昨天她说太多,没有喝足够的水她现在有一个喉咙痛

求little talks 歌词(带中文 )

Little Talks作词:Arnar Renkranz Hilmarsson、Brynjar Leifsson、Nanna Brynd Hilmarsdtir、Ragnar Rhallsson作曲:Arnar Renkranz Hilmarsson、Brynjar Leifsson、Nanna Brynd Hilmarsdtir、Ragnar RhallssonHey! Hey! Hey!I don"t like walking around this old and empty houseSo hold my hand; I"ll walk with you, my dearThe stairs creak as I sleep; it"s keeping me awakeIt"s the house telling you to close your eyesSome days I can"t even trust myselfIt"s killing me to see you this way"Cause though the truth may vary,this ship will carry Our bodies safe to shoreHey! Hey! Hey!There"s an old voice in my head that"s holding me backWell tell her that I miss our little talksSoon it will all be over and buried without pastWe used to play outside when we were young, and full of life and full of loveSome days, I feel like I"m wrong when I am rightYour mind is playing tricks on you, my dear"Cause though the truth may vary,this ship will carry Our bodies safe to shore.转载来自 ※Mojim.com 魔镜歌词网 Hey! Don"t listen to a word I say Hey!The screams all sound the same Hey!Though the truth may vary,this ship will carry Our bodies safe to shoreYou"re gone, gone gone away; I watched you disappearAll that"s left is a ghost of youNow we"re torn, torn, torn apart; there"s nothing we can doJust let me go; we"ll meet again soonNow wait, wait, wait for me; please hang aroundI"ll see you when I fall asleepHey! Don"t listen to a word I say Hey!The screams all sound the same Hey!Though the truth may vary,this ship will carry Our bodies safe to shoreDon"t listen to a word I say Hey!The screams all sound the same Hey!Though the truth may vary, this ship will carry Our bodies safe to shoreThough the truth may vary, this ship will carry Our bodies safe to shoreThough the truth may vary, this ship will carry Our bodies safe to shore嘿!嘿!嘿!我不喜欢这个古老而空的房子里走来走去因此,握住我的手,我会陪着你走,我亲爱的楼梯吱吱我睡觉,让我清醒这是房子告诉你闭上你的眼睛有些日子里,我什至不能相信自己这是杀害我看你这样因为,虽然真相可能会有所不同,此船将承载我们的身体安全到岸嘿!嘿!嘿!有一个苍老的声音在我的头,抱着我告诉她,我很怀念我们的小会谈不久,它都将结束并没有过去埋我们在外面玩,当我们年轻,充满生机,充满爱心有些日子,我觉得我错了,当我是正确的你的心是在捉弄你,我亲爱的因为,虽然真相可能会有所不同,此船将承载我们的身体安全到岸。转载来自※Mojim.com魔镜歌词网嘿!不要听一个字,我说嘿!的尖叫声音同嘿!虽然真相可能会有所不同,此船将承载我们的身体安全到岸你走了,走了走了,我看着你消失剩下的就是你的鬼现在,我们的心被撕裂,撕裂,撕裂,没有什么我们可以做的只要让我走,我们会再次见面。现在等待,等待,等待我,请流连当我睡着的时候,我会看到你嘿!不要听一个字,我说嘿!的尖叫声音同嘿!虽然真相可能会有所不同,此船将承载我们的身体安全到岸不要听一个字,我说嘿!的尖叫声音同嘿!虽然真相可能会有所不同,此船将进行我们的身体安全到岸虽然真相可能会有所不同,此船将进行我们的身体安全到岸虽然真相可能会有所不同,此船将进行我们的身体安全到岸如果喜欢请采纳谢谢O(∩_∩)O~~

Skywalk的《Weeds》 歌词

歌曲名:Weeds歌手:Skywalk专辑:Larger Than LifeWe came across the North Sea with our carriers on our kneesWound up in some holding camp somewhere outside Leeds.Because we do not care to fight, my friends - we are the weeds.Because we got no homes they call us smelly refugees.Ah.We are weeds, vegetation, dense undergrowth.Thru" cracks in the pavement: there weeds will grow - the places you don"t go.This cut-price dairy produce that turns our bones to dust.You want some entertainment?Go on, shove it up me - if you must.Make believe you"re so turned on by planting trees & shrubsBut you come round to visit us when you fancy booze "n" drugs.Ah.We are weeds, vegetation, dense undergrowth.Thru" cracks in the pavement: there weeds will grow - the places you don"t go..If you think it"s a crimeWe"d like to get you out of your mind.It"s just a matter of time, yeahWe"d like to get you out of your mind.Gonna cut you down in your prime, yeahWe"d like to get you out of your mind.For a little time: for all time.http://music.baidu.com/song/7931958

Talk in circles 说话绕圈子

我们今天来讲一个描绘言谈方式的习惯用语: talk in circles。 Circle意思是园圈,中文也有“说话绕圈子”的说法,意思是说话不直截了当,迷惑听话的人。 我们通过个例子来体会英文talk in circles是不是含义相同。我们知道要是一名辩护律师承*据不利于当事人的案子,那他作辩护时就可能会采取迂回战术,以混淆法官和陪审团的视听。下面这段话正是这样的例子。 例句:He was caught standing over the victim with a smoking gun. His lawyer talked in circles trying to confuse the jury. But they still remembered that smoking gun and found him guilty. 他说:他被逮住的时候脚下就躺着被害人,手上还握着冒烟的手枪。他的律师绕着圈子说话,试图把陪审团弄糊涂,但是陪审团还是忘不了那把冒烟的手枪,仍然判定他有罪。 他的罪证确凿,所以律师想为他开脱罪责就不能实话直说了,只得转弯抹角地误导听众。这就是talk in circles这个习惯用语的意思。

Walking is ___ than jogging.slower 还是 more slowly?

选择 slower 答案

sppech,talk,lecture作名词的比较

speech是指正式的演讲lecture是讲座 上课的意思talk是谈话 若作演讲义则是非正式的人数不多的小型谈话的意思

四年级下册英语58的 letstalk的汉语

Lets talk:让我们谈谈let stalk:让秸秆

teen talk是什么意思

Teen Talk 青少年论坛teen=teenager 10-19岁的年轻人

句子翻译 I walked to the door and knocked , " Just a minute ,” answered a weak ,

Iwalkedtothedoorandknocked,"Justaminute,”answeredaweak,elderlyvoice.我走到门前,敲了敲门,“就一分钟,”一个虚弱,苍老的声音答复了我。

请问有谁知道Teen Talk是什么意思?紧急,谢谢!

愤怒的演讲

realshades和realkids区别

前者是总品牌,后者是子品牌。蓝光分为有害蓝光和有益蓝光.片面追求超高的蓝光阻挡效率并不好.如果有益蓝光被吸收会影响大脑褪黑素的分泌.影响睡眠。

shadez和realkids眼镜怎么样

SHADEZ源自瑞士的儿童专业防护眼镜品牌以一体鼻托、可弯曲防滑镜腿、抗碎镜片等产品而享誉世界产品涵盖儿童太阳镜和防蓝光眼镜 品牌希望把炫酷、安全、有型的理念传输给更多中国家长和儿童。SHADEZ专注于设计、研发、生产、销售儿童眼镜,由于儿童瞳孔和晶状体的特殊结构,以及更多的户外活动,使他们比承认更容易受到紫外线的刺激和伤害,为了保护孩子们的视力免受损伤,SHADEZ儿童太阳镜由此诞生EAL KIDS所有的款式的太阳镜,能阻隔紫外线,也就是阻隔伤害视力的UVA和UVB,并采购无毒材质,不含双酚A、铅以及二甲酸盐等有害物质.REAL KId S的FLEx- FIx镜框架采用热塑性可扭曲的聚酯弹性体,这种贴合脸型的设计不容易掉落

talk show是什么意思

talkshow是脱口秀的意思。脱口秀(美式英文:TalkShow,中文名字是英文之音译),一般脱口秀都有一系列的嘉宾,通常由有学问的或者对那档节目的特定问题、有特殊经验的人组成。脱口秀有松散性和幽默性等特点。在我国,继20世纪90年代中期中央电视台推出《实话实说》之后,许多电视台也纷纷上马新式的谈话节目,令人目不暇接。我国的相声艺术就被西方国家认为是“脱口秀”。脱口秀(US-TalkShow,Brit-ChatShow),亦称为谈话节目,是指一种由观众聚集在一起讨论主持人提出的话题的广播或电视节目。

talking at cross purposes什么意思

talking at cross purposes在交叉的目的交谈双语对照例句:1.We"ve been talking at cross purposes. I"m afraid so. 我们竟然在误会之中谈起天来了.我恐怕是.2.I think we"re talking at cross purposes; that"s not what I meant at all. 我想我们是说到两下里去了,我根本不是那个意思。

求高人~I walked too much yesterday and ___are still aching now.

A表达的意思是整条腿的肌肉;B表达的意思是腿的运动部分肌肉。

索尼walkman上的zap和bass是干什么用的

ZAP没啥用 自动选曲的 BASS是开启重低音

shelter alan walker中文歌词

You are the sun in my skyEven when the stars collideYou are gonna make me shineYou make me shine colorsI"m going through every road IThrough road of my lifeI will be by your sideAnd I"ll be there when you call (Yeah)And then we know pain at allAnd I"ll be, be your shelterThe shelter from the stormAnd there always be your shelterI"ll be there if you fallAnd if you walk the lonely roadKnow that you"re not alone yetCause I"ll be, be your shelterThe shelter from the stormWhen you rains coming downTill you can"t stand your groundI won"t let you drownAnd I"ll be there when you call (Yeah)And then we know pain at allAnd I"ll be, be your shelterThe shelter from the stormAnd there always be your shelterI"ll be there if you fallAnd if you walk the lonely roadKnow that you"re not alone yetCause I"ll be, be your shelterThe shelter from the storm (Storm)The shelter from the (Storm, storm)The shelter from the storm你是我天空中的太阳即使当星星碰撞你会让我闪耀你让我闪耀的颜色我要走过每一条路通过我生命的道路我会在你身边当你打电话的时候我会在那里(是的)然后我们知道所有的痛苦我会是你的庇护所暴风雨中的庇护所那里永远是你的庇护所如果你坠落,我会在那里如果你走在孤独的路上知道你还不孤单因为我会是你的庇护所暴风雨中的庇护所当你下的雨直到你不能站在你的地面我不会让你淹死当你打电话的时候我会在那里(是的)然后我们知道所有的痛苦我会是你的庇护所暴风雨中的庇护所那里永远是你的庇护所如果你坠落,我会在那里如果你走在孤独的路上知道你还不孤单因为我会是你的庇护所暴风雨(风暴)的庇护所避风港(风暴,风暴)暴风雨中的庇护所

Jr. Walker & The All Stars的《Shotgun》 歌词

歌名:Shotgun歌手:Jr. Walker & The All Stars地区:United States of America 美国 风格:放克 Funk,都市音乐 Urban 语种:英语 发行时间:2008-04-18发行公司:环球唱片歌词:I said, shotgunShoot "em "fore he runs, nowDo the jerk, babyDo the jerk, nowHey!Put on yo" red dressAnd then you go downtown, nowI said, buy yourself a shotgun, nowWe gonna break it down, baby, nowWe gonna load it up, baby, nowhen you shoot him "fore he run, nowI said, shotgunShoot "em "fore he run, nowDo the jerk, babyDo the jerk, nowHey!ShotgunShoot "em "fore he run, nowDo the jerk, babyDo the jerk, nowYeah!Put on yo" high-heel shoesI said, we goin" down hereAn listen to "em play the bluesWe gonna, dig potatoesWe gonna, pick tomatosI said, shotgunShoot "em "fore he run, nowDo the jerk, babyDo the jerk, nowYeah!I said it"s, Twine timeI said it"s, Twine timeI said it"s, Twine time"Hey!"Wailin" out the blues!"歌词大意:我说,猎枪射击在他们跑之前,现在做掉那混蛋,宝贝做掉那混蛋,现在嘿!穿上你的红色连衣裙然后你去市中心,现在我说,买自己一把枪,现在我们要打破它,宝贝,现在我们要把它装起来,宝贝然后你射击,在他跑之前,现在我说,枪他跑了,现在就射击做那个混蛋,宝贝做那个混蛋,现在嘿!猎枪他跑了,现在就射击做掉那混蛋,宝贝做掉那混蛋,现在是啊穿上你的高跟鞋我说,我们要在这里听他们演奏蓝调我们要去挖土豆我们要摘西红柿,我说,枪他跑了,现在就射击做那个混蛋,宝贝做那个混蛋,现在是啊我说是,缠绕时间我说是,缠绕时间我说是,缠绕时间"嘿!“悲伤的蓝调!”

劳拉替尼说明书 alk突变三代靶向药劳拉替尼

劳拉替尼说明书 alk突变三代靶向药劳拉替尼 药品名称:劳拉替尼(Lorlatinib) 商品名称:Lorbrena 适应病症:ALK阳性非小细胞肺癌 给药途径:口服 药物类型:靶向治疗药物 药物规格:25mg,100mg;片剂 中国是否上市:是 Lorlatinib(劳拉替尼)是辉瑞公司开发的一种新型、可逆、强效小分子ALK和ROS1抑制剂,其对ALK已知的耐药突变均具有很强的抑制作用,因而被誉为第3代ALK抑制剂。 2018年11月2日,FDA批准了Lorlatinib劳拉替尼,用于ALK阳性转移性非小细胞肺癌(NSCLC)患者,其疾病在克唑替尼和至少一种其他ALK抑制剂(阿来替尼、色瑞替尼)治疗后进展的患者。 无论既往用过几种靶药或者化疗过,劳拉替尼始终能够作为ALK耐药最终保底的药物。 劳拉替尼也在各线治疗展示强劲的炉内控制力。的NCCN指南将劳拉替尼列为三线保底治疗推荐。 劳拉替尼在Ⅱ期临床试验中显示出对肺肿瘤和脑转移瘤的持久的疗效。先前接受过2-3种ALK抑制剂治疗后的患者客观缓解率达39%,颅内缓解率达48%。 Lorlatinib的获批基于Ⅱ期临床试验,我整理完整数据如下: 对于ALK阳性的初治NSCLC患者,ORR高达90%,颅内ORR达到了75%;对于ALK阳性且先前接受过克唑替尼治疗的患者,ORR为69%,颅内ORR达到了68%;对于ALK阳性且先前接受过克唑替尼以外的其它ALK抑制剂治疗的患者,ORR为33%,颅内ORR达到了42%;对于ALK阳性且先前接受过2-3种ALK抑制剂治疗的患者,ORR为39%,颅内ORR达到了48%;对于ROS1阳性的经治患者,ORR为36%,颅内ORR达到了56%。 用药前,先基因检测 对于肺癌靶向药的选择,患者必须清楚的是用药前一定要先检测,精准靶向治疗才是晚期NSCLC诊疗的大势所趋。我们要检测,不要猜测。没有ALK基因突变,那么请放弃使用阿来替尼。 ALK融合基因检测的材料主要来源于手术标本、CT引导下活检组织、纤维支气管镜活检组织、胸水细胞包埋组织等。ALK基因重排常用的检测方法目前常用的有:荧光原位杂交、免疫组织化学、反转录-聚合酶链式反应。 上述方法于目前大部分医院病理科均可开展,各大基因检测公司也能检测。但是,患者选择基因检测机构时一定要注意,选择可信赖的基因检测公司。因为不同的基因检测公司,检测的准确度是不同的,要选择肿瘤医院或者国家机构认证的大型基因检测公司。了解国内外基因检测机构登录全球肿瘤医生网咨询。 劳拉替尼耐药后,怎么办? 研究表明,几乎所有的靶向药治疗后都会出现耐药问题,只是有的人耐药早,有的耐药晚。 那么,患者耐药后,一定要再重新进行一项基因检测,寻找发生耐药的机制,对症治疗。 若发生的仍为ALK其他位点的基因突变,可以换用其他ALK抑制剂。由于劳拉替尼是其他ALK抑制剂的保底药物,再没有其他标准选择的时候可以寻找临床试验,尝试新的治疗机会。 若发生的是驱动基因旁路激活突变,包括EGFR旁路激活,KIT基因扩增,或其他驱动基因突变;若是EGFR、KIT或其他驱动突变导致的旁路激活,需要针对这些靶点突变用相应的靶向药。 耐药原因不明的,也可以再取组织进行活检,看看是否是发生了组织学变化,这时候可能就需要化疗或者医生推荐的其他治疗手段。 用法用量 建议剂量:口服每天一次,每次100mg,每天在同一时间服用。忘记服用时可补服,除非距离下一次服用的时间少于4小时,不可同时服两次分量。 剂量减少调整:第一次剂量减少可调整至每天一次75mg;第二次剂量减少可调整至每天一次50mg。若无法承受每天50mg的剂量,则永久停止。 呕吐的情况下不用补服,照常在下次才服用就可以。 用药注意 可以与食物同服,也可不同服。 药片整个吞下,不要压碎或咀嚼。 许多药物都会影响阿来替尼疗效,包括处方药和非处方药、维生素和中药产品,服用其他药物前请与主治医生沟通。 服药期间需有效避孕,孕期及哺乳期禁止服用劳拉替尼。 若有过敏反应的迹象,如荨麻疹、呼吸困难、脸部,嘴唇,舌头或喉咙肿胀,尽快就医。 常见不良反应 水肿,周围神经病变,认知功能,呼吸困难,疲劳,体重增加,关节痛,情绪影响和腹泻。
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