che

选择正确机型和安装磁盘,安装macOS Patcher后关机,然后再开机(重新启动可能会卡死)后成功进入系统设置页面。

内存不能为written的问题是一个非常复杂的问题，造成的原因是多方面的，有硬件的原因，也有软件的原因，一时半会儿很难搞的清楚。就我个人的理解，大多与使用非原版的系统而产生的不稳定性有关，轻易很难修复。你可以试着从一下方面寻找原因：1.内存条坏了或与主板不兼容更换内存条2.双内存不兼容使用同品牌的内存或只要一条内存3.内存质量问题更换内存条4.散热问题加强机箱内部的散热5.内存和主板没插好或其他硬件不兼容重插内存或换个插槽6.硬盘有问题更换硬盘7.驱动问题重装驱动,如果是新系统,应先安装主板驱动8.软件损坏重装软件9.软件有BUG打补丁或更新到最新版本10软件和系统不兼容给软件打上补丁或是试试系统的兼容模式11软件和软件之间有冲突如果最近安装了什么新软件,卸载了试试12软件要使用其他相关的软件有问题重装相关软件,比如播放某一格式的文件时出错,可能是这个文件的解码器有问题13病毒问题杀毒14杀毒软件与系统或软件相冲突由于杀毒软件是进入底层监控系统的,可能与一些软件相冲突,卸载试试15系统本身有问题有时候操作系统本身也会有BUG,要注意安装官方发行的更新程序,象SP的补丁,最好打上这里建议首先游戏不要装在C盘并卸载冲突的防火墙或者杀软修复系统漏洞打上所有补丁最后清理注册表信息并重启电脑

诺基亚的手机破解就是指破解它Symbian系统在安装软件的权限问题，跟证书有关，因为一些程序不被系统里的证书所认可，可能会对系统造成危害，所以安装这样的程序时系统是拒绝安装的。 但是有些程序我们自己知道是安全的，这时想安装就可以有种途径，一：制作手机证书及密钥，对要安装软件签名通过（也是骗过）系统的安全检验；二：破解手机系统，这个比较麻烦，可以参考<a href="http://bbs.blueshow.net/thread-610438-1-1.html" target="_blank">http://bbs.blueshow.net/thread-610438-1-1.html</a>，但是建议初接触智能手机的不要急着去破解，多去塞班论坛玩，等玩熟了再破解。所以现在还是建议你签名对于制作证书问题，可以帮你制作，你在待机画面按*#06#，查到手机串号发到我邮箱675891456@qq.com,收到后6小时后会把证书密钥及签名软件教程发给你的。。。

就是有个文件名就是这个，你点这个进去

重新下载

ddraw.dll这个文件被病毒感染了。杀完毒没修复！ 这个问题 用金山网盾的一键修复能完美解决~百度搜~一下：金山网盾 （这四个字），你就会看到醒目的官方下载。下载之，安之，打开按 一键修复 之，扫描完了，按立即处理解决之。

可能程序不兼容， 可以更换个版本试试。另外建议参考下程序对配置的要求。或者右键需要运行的程序 选择兼容性 用兼容模式运行试试。

双击“我的电脑”，打开之后，点菜单下：工具——文件夹选项——文件类型——新建——弹出对话框，输入 .exe——高级——在下面的框里面选中“应用程序”——确定。 这样就行了。 参考资料： http://hi.baidu.com/cad%5Fanswer/blog/item/a718954f30251e01b3de05b0.html 去网上下载补丁，不行的话就重装

楼主，你好！你所说的这种情况我也遇到过，不过后来重新启动了游戏一两次就进去了，我比较幸运，呵呵！我觉得嘛，可能有以下几种原因所致：1.你的网速太慢;2.游戏安装文件丢失,重装一下游戏应该就OK；3.下载游戏的时候下了病毒,也有可能是你的电脑中病毒了，用杀毒软件扫描下你安装游戏的那个目录.建议您检查网络连接是否正常，如果是使用路由器连接多台电脑同时上网，请调整路由器或者代理网关的设置，将防火墙的规则去除。每个路由器的设置方法可参考使用说明或使用GOOGLE进行搜索相关文章进行操作。建议您也可以使用360安全卫士清除电脑中安装的恶意软件和插件，清除一下电脑中是否存在不安全的第三方软件。在进行游戏时关闭和游戏无关的程序，或尝试关闭防火墙（包括系统自带的）、杀毒软件等系统监控程序后再登录游戏看看。以下是鄙人的一些经验，希望对你有用！一：重新启动电脑或者把你原来的卡丁车文件包复制后粘贴到另一个磁盘,再从那里进去就行啦二：应该是你的杀毒软件和跑跑冲突了.因为有的杀毒软件会限制或关闭BIT.所以建议先把杀毒软件关了在进看看.如果可以进就退出来把杀毒软件里的设置改一下三：试着关了一些不必要的程序四：可能你的网络连接不太正常五：可能是跑跑程序与你的系统自带的程序发生了冲突你的操作系统是不是VISTA这是由于跑跑卡丁车与vista存在兼容性问题。Vista操作系统为了安全，限制了很多操作，尤其是启用UAC帐户管理后软件的兼容性问题就接踵而来。可以用以下的方法解决问题：首先，跑跑卡丁车使用的是韩国公司nProtect加密技术，需要使用内核驱动服务运行，所以会因为权限问题而造成无法启动服务。然后，下载安装安装最新的显卡驱动和下载安装最新的跑跑卡丁车的客户端（需要以已管理员身份运行安装）。最后，如果还没有解决的话，可以进入安装跑跑卡丁车的目录下，将“NMService.exe”和“KartRider.exe”，文件选中单击鼠标右键，选择以管理员方式运行，最后在属性里将其修改为“以XPSP2兼容方式运行”。五,也有可能是你的跑跑程序的某个文件让你错删了,你不妨把跑跑卸载了，然后重新安装一下。。希望能帮到你，祝你游戏愉快！

从新安装

关掉PATCHER.EXE，然后重新运行更新包。如果再不行那就是更新包下载的过程中出错了，需要重新下载更新包。另外提醒楼主记得查看更新包升级版本编号和本身游戏编号，不要有落差，否则也会更新不了

PATCHER就是补丁啊，升级用的，游戏有了新版本更新就要用这个啊

维修工人····吧

把patcher.exe应用程序运行完,按照安装提示进行,应该没有什么问题.

你这个应该是游戏的应用程序.到游戏目录下面找到个叫patcher的文件运行即可.希望能帮上您.

进程文件: patcher.exe 进程名称: patcher.exe 进程分析: 通常为应用软件或网络游戏的升级

进程名称: patcher.exe 进程分析: 通常为应用软件或网络游戏的升级

可能在存储的时候文件破损!如果没转存的话看看是不是播放器有问题换个试试!热血十年典藏账号(注册)tg.sdo.com/740217593电脑常识

近日备受瞩目的“大黄蜂”——雪佛兰Camaro公布了价格，据悉即将国内即将进口的“LSCoupe”到顶级的性能版“2SS”MSRP售价区间在2.2245--3.3430万美元折合人民币月15万元--22万元左右，该价格也是Camaro售价最低的车型，加上关税预计国内售价高达47万元，这个价格和卡迪拉克CTS3.6车型相差不多。

就是所谓的《变形金刚》上的大黄蜂！暂时中国只引进一部，是为了配合电影《变形金刚》的上映，并且在电影首映之后拍卖，估计要到150万，因为此车还未批量生产，待批量生产之后，也要到40-60万之间，因为还要考虑排量问题，排量大的，自然就贵

变形金刚里面的大黄蜂通用集团于2006年在北美车展发表概念车，并于同年证实新Camaro上市的宣言后，由概念车正式演化为量产车的Chevrolet Camaro

雪佛兰 柯迈罗（俗称大黄峰）

手表和珠宝

AccpTeacher类和SoftwareTeacher类关系呢？

1、pull拉取远程仓库上的代码。2、修改本地代码。3、然后commit，commit时候选择你要提交的你修改过的文件填写提交的作者，日期，说明信息。这样你本地仓库代码已经提交。4、将本地仓库和远程仓库进行同步，使用push命令推送到远程仓库即可。以上就是gitchraken显示conflictpreventscheckout的解决方法。

在黑暗中搏斗

歌曲名:Roll With The Punches歌手:Lenka专辑:ResturlaubLenka - Roll With The PunchesRoll, roll with the punchesRoll, roll with the punchesThat really hurt meLike a fist to the face I wasn"t readyTo be knocked out of placeSuddenly everything I was sure ofSinking below the depths of the surfaceIt"s unexpected, it usually isWhen you"re rejected, or you take a hitSuddenly everything"s thrown in a spinNo time to grow a thicker skinWhat kind of situation am I in now?When life tries to knock all the wind out of youYou"ve got to roll, roll, roll with the punchesIf all life offers is black and blueYou"ve got to roll, roll, roll with the punchesLittle weapons over the phoneThey like to threaten the life that I knowThey say get over here and get into the ringBut I"m not really much a fighterMy mechanisms of defense are downAnd my resistance is out on the townI was alarmed by your attackThis isn"t a boxing matchBut I"ll be damned if I ever let you winWhen life tries to knock all the wind out of youYou"ve got to roll, roll, roll with the punchesIf all life offers is black and blueYou"ve got to roll, roll, roll with the punchesWhen all I want is a little stabilitySome time without any bruisesYou go and tell me the things that I don"t want to hearPutting your fist into my earsFilling me up with the dread and the fear leaving you all in piecesSuddenly everything"s thrown in a spinNo time to grow a thicker skinWhat kind of situation am I in now?Oh when life tries to knock all the wind out of youYou"ve got to roll, roll, roll with the punchesIf all life offers is black and blueYou"ve got to hold, hold, hold your head up highWhen life tries to knock all the wind out of youYou"ve got to roll, roll, roll with the punchesIf all life offers is black and blueYou"ve got to roll, roll, roll with the puncheshttp://music.baidu.com/song/9335006

世事难料，兵来将挡。意指事情千变万化，一定要懂得随机应变。

Lenka - Roll With The PunchesRoll, roll with the punchesRoll, roll with the punchesThat really hurt meLike a fist to the face I wasn"t readyTo be knocked out of placeSuddenly everything I was sure ofSinking below the depths of the surfaceIt"s unexpected, it usually isWhen you"re rejected, or you take a hitSuddenly everything"s thrown in a spinNo time to grow a thicker skinWhat kind of situation am I in now?When life tries to knock all the wind out of youYou"ve got to roll, roll, roll with the punchesIf all life offers is black and blueYou"ve got to roll, roll, roll with the punchesLittle weapons over the phoneThey like to threaten the life that I knowThey say get over here and get into the ringBut I"m not really much a fighterMy mechanisms of defense are downAnd my resistance is out on the townI was alarmed by your attackThis isn"t a boxing matchBut I"ll be damned if I ever let you winWhen life tries to knock all the wind out of youYou"ve got to roll, roll, roll with the punchesIf all life offers is black and blueYou"ve got to roll, roll, roll with the punchesWhen all I want is a little stabilitySome time without any bruisesYou go and tell me the things that I don"t want to hearPutting your fist into my earsFilling me up with the dread and the fear leaving you all in piecesSuddenly everything"s thrown in a spinNo time to grow a thicker skinWhat kind of situation am I in now?Oh when life tries to knock all the wind out of youYou"ve got to roll, roll, roll with the punchesIf all life offers is black and blueYou"ve got to hold, hold, hold your head up highWhen life tries to knock all the wind out of youYou"ve got to roll, roll, roll with the punchesIf all life offers is black and blueYou"ve got to roll, roll, roll with the punches

情况变了，我们得兵来将挡！Roll with the punches实际上是逆来顺受的意思，在这里兵来将挡这样翻译比较合适！

roll with the punches（拳击手）避让对方打击以减轻受打击的力; 以上结果来自金山词霸例句:1.Maturity helps you roll with the punches a little more, "she says. 她说：“成熟有助于一个人应对各种压力。”

roll with the punches英翻中：逆来顺受

从容应对困难

不会动真格的。（不会带来任何打击）

情况变了，我们得兵来将挡！Roll with the punches实际上是逆来顺受的意思，在这里兵来将挡这样翻译比较合适！

水果混合饮料

他们扭打在一起。

pull no punches用力打网络释义1. 手下留情2. 不客气,动真格的例句:1.In his experience, the most effective coaches pull no punches: "if people know youhave their best interests at heart, they can take honest criticism no matter how it"sgiven. 按照他的经验，最有效的教练从来都是毫不留情的：“如果大家知道，你真诚地批评完全是为了他们的最大利益，他们应该都能够接受，不论你采取哪种方式。

pull your punches故意不用全力打(故意不猛烈攻击)punchesn.冲床; 拳打; 猛击( punch的名词复数 ); 力量vi.; v.用拳猛击( punch的第三人称单数 ); 打孔; 例句:1.But when it comes to deploying social-networking tools, first round punches above its weight. 不过在配置社交网络工具方面，首轮资本公司的表现远远超过它的规模。2.Mazda punches above its weight with smart designs that are right-sized but seldom scores a knockout. 马自达（Mazda）一向以尺寸合适的聪明设计以小制胜，但是很少能真正获得完胜。

topullnopunches。topullnopunches，这是指毫不保留地告诉别人你的看法。punch这个字的一种解释就是拳击。topullnopunches这个俗语使人脑子里顿时出现一个拳击场里两个拳击手扭成一团，互相攻打对方，而对方设法回避的形像。但是topullnopunches这个俗语并不是用在拳击方面的。下面的例子说明在日常生活中怎么用这个俗语：例句-1:"whenisawmybrotherjoe,ididn"tpullanypunches--itoldhimtostopdrinkingandgooutandfindajob."这句话翻成中文的意思是：“当我见到我哥哥乔的时候，我毫不保留地对他说，不要再喝酒了，还是出去找个工作吧。”人们要想毫无保留地对对方讲心里话的时候往往会很犹豫，怕伤害别人。但是，在有的情况下，你绝不会犹豫，就像下面这个例子里的这个人：例句-2:"ipullednopuncheswheniwenttoseetheautodealerwhosoldmesuchalousycar.itoldhimheoughttobeashamedtochargesomuchforacarthathadsomanythingswrongwithit.no,hedidn"tgivememymoneyback,butisurefeltbetterafterwards."这个人说：“那个汽车商卖给我的这辆汽车毛病太多了。我去看他的时候毫不客气地对他说，卖这么次的车给我还收我那么多的钱，你自己应该感到害臊。虽然他并没有把钱还给我，可是，说了这些话我感到痛快多了。”

不是谚语。（开车的时候）看后视镜确认一下行车路线。

它会把你带入21世界且不用在观后镜中检查你行驶的路线.

adopt approaches采取办法双语例句1The Special Rapporteur recommends that the Council invite Member States toadopt approaches in the promotion of dialogue between cultures, civilizationsand religions taking into consideration:特别报告员建议理事会根据以下几点，请各会员国采取措施促进文化、文明和宗教间的对话：

能否帮忙校对一下竣工图？

It is the icon of Accor now. Bernache is a kind of wild goose in Canada.

如果我成为一个老师

innisfree orchid enriched cream悦诗风吟兰花奶油-----------------------------------如有疑问欢迎追问！满意请点击右上方【选为满意回答】按钮

歌曲名:California歌手:Joni Mitchell专辑:BlueCaliforniaEgil OlsenI Am A Singer/songwriter40 000 feet above the groundi"m on my way to california离地面四万英尺，我在去加利福尼亚的路上i have always wanted to go there我一直都想去那里now i"m comin flyin through the air而今我正飘然飞来bought myself a new guiar and spent the rest on motels and a rental car买了一把新的吉他，让剩下的钱留给住宿和交通pretty girls and oranges and superstars neon lights and sunshine blocking out the dark漂亮姑娘、桔子和明星，霓虹灯和阳光隔开了黑暗even the bum seem to have a lot of fun连流浪汉看起来都充满欢乐dancing on the sidewalk in the sun在人行道的日光里舞蹈good things are comin for the boy on the run好事情来给奔跑着的男孩this is where a new era begun一段崭新的生活在这儿到来wrote a load of songs inside my mind while driving round in california在朝向加州行驶途中打了下许多歌曲的腹稿some of them might someday end up on the air这些歌中有些会不再播放while some of them got lost over there有些则会消逝在别处this is the one that I started to hum这首歌我则把它唱起来gazing out the windshield at the sun凝视着挡风玻璃外面的太阳good things are comin for the boy on the run好事情来给奔跑着的男孩this is where a new era begun一段崭新的生活在这儿到来by Cμhttp://music.baidu.com/song/2177111

外界刺激 (如药物、紫外线和电离辐射) 和内源性自由基和活性氧 (ROS)会直接或者间接地损伤蛋白质、脂质和 DNA 等细胞成分，为了抵御这些不利影响，机体形成了一套复杂的氧化应激应答系统来缓解细胞所受的损害。而 Nrf2 ， 作为 调控抗氧化应激的一种关键转录因子，在诱导机体的抗氧化应答中起着重要作用 ，如调节氧化还原平衡、药物代谢和排泄、能量代谢、铁代谢、氨基酸代谢、生存、增殖、自噬、蛋白酶体降解、DNA 修复和线粒体生理机能。另外，Keap1-Nrf2 系统已成为癌症和神经退行性疾病以及许多自身免疫和炎性疾病的重要治疗靶点。 Nrf2 的自我介绍 ：大家好，我是 Nrf2~我是 Cap"n"collar(CNC) 转录因子家族成员，我的“身体”由七个 Neh 域 (Nrf2 ECH 同源结构域) 组成，每个域具有不同的功能，如 Neh1 CNC-bZIP 域负责与 small Maf (sMAF) 蛋白结合和二聚化；Neh2 结构域通过 DLG 和 ETGE 基序介导与 Keap1 的相互作用；Neh4、Neh5 和 Neh3 域对于 Nrf2 的反式激活非常重要；Neh6 结构域是一个富含丝氨酸的区域，可调节我的稳定性。大家猜猜，我是怎么被激活的呢？                                                                            Nrf2 的激活“大戏” 1、经典途径——Keap1-Nrf2 途径 说到 Nrf2 的经典激活机制，不得不提一提 Nrf2 老搭档——Keap1 (Kelch ECH 相关蛋白 1)。Keap1 是一种 Cullin3 (Cul3) 依赖性的 E3 泛素连接酶复合物的底物衔接蛋白，可与 Cul3 和 Rbx1 组装成功能性 E3 泛素连接酶复合物 (Keap1-Cul3-E3)，进而对 Nrf2 进行调控。Keap1 含有三个功能域，包括一个 BTB 结构域，一个 IVR 和一个 Kelch 或 DGR 结构域。BTB 结构域结合 Cul3，是 Keap1 二聚化所必需的。Kelch/DGR 结构域可与上面提到的 ETGE 和 DLG 基序相互作用，这对于维持 Nrf2 和 Keap1 之间的相互作用至关重要。IVR 连接了 BTB 和 Kelch/DGR 结构域，含有一些可调节 Keap1 的活性的半胱氨酸残基。 在正常的生理条件下，Keap1-Cul3-E3 泛素连接酶靶向位于 Nrf2 N 端的 Neh2 结构域 (位于 DLG 和 ETGE 基序之间) 的多个赖氨酸残基，并促进泛素化，随后泛素化的 Nrf2 被递送至 26S 蛋白酶体进行降解。[PS: DLG 和 ETGE 与 Keap1 中的 Kelch 域相互作用，一般称为“铰链和闩锁” (Hinge-and-latch model) 模型]。 而暴露于 ROS、亲电胁迫会使 Keap1 中特定的半胱氨酸残基被修饰，引起 Keap1-Cul3-E3 泛素连接酶的构象变化，干扰 Nrf2 泛素化，随后 Nrf2 易位至细胞核，通过与 sMAF 蛋白的异二聚化作用结合到靶基因的 ARE/EpRE (抗氧化反应元件/亲电响应元件) ，诱导一系列细胞保护性基因表达，如 NQO1 、 GST 、 HMOX1 、 GCL 、 GSH 等。2、非经典途径——自噬-溶酶体途径 除 Keap1-Nrf2 途径外，Nrf2 激活的非典型机制，即 自噬-溶酶体途径是由自噬功能障碍驱动的 ，自噬-溶酶体途径在介导氧化应激中也起关键作用。自噬是一种严格调控的细胞降解途径，负责清除受损的蛋白质和细胞器，包括氧化受损的蛋白质和功能异常的线粒体，自噬可以是非选择性的，也可以是选择性的。p62/SQSTM1 (以下称 p62) 是一种选择性自噬的经典受体，用于降解泛素化的底物。p62 参与许多信号转导途径，其中包括 Keap1-Nrf2 途径。自噬功能障碍 (如 Atg5 、 Atg7 缺失，*毒物环境等引起)则会导致自噬衔接蛋白的 p62 的积累。由于 p62 是能与许多蛋白相互作用的多域蛋白，它的积累会导致许多结合蛋白的隔离和功能丧失，包括 Keap1。研究表明，p62 与 Nrf2 竞争结合 Keap1，这种相互作用使 p62 可以将 Keap1 螯合到自噬体中，从而阻止了 Keap1 介导的 Nrf2 降解，导致 Nrf2 通路激活。                                                                      Nrf2 在癌症中的两面做派 在生理条件下，Nrf2 维持细胞的氧化还原稳态，并发挥抗炎功能和进一步的抗癌活性，从而支持细胞存活。因此，Nrf2 的激活在癌症化学预防中很重要。但是，Nrf2 的过度活化也会赋予癌细胞多种优势，比如保护癌细胞免于凋亡和衰老，促进细胞生长，介导癌细胞对化疗和放疗的抗性等。1、Nrf2的阳光面——激活抑制肿瘤发生 Nrf2-Keap1 途径的激活是抗肿瘤发生的最重要机制之一。通过靶向 Nrf2/ARE 途径来调控基因，进而发挥化学预防作用的一些化合物，不仅包括合成化合物如 Oltipraz ，还有一些植物来源的化合物，例如 Sulforaphane 、 Curcumin 、 Resveratrol 等。 2、Nrf2 的阴暗面——组成型激活促进癌症的发展 一些研究表明在各种癌症中 Nrf2 信号通路组成性激活会促进癌细胞的生长和增殖，阻止细胞凋亡，增强癌症干细胞 (CSC) 的自我更新能力，更重要的是，可增强癌细胞的化学耐药性和放射抗性。因此，阻断 Nrf2 信号是一种有前途的癌症治疗方法，特别是对于 Nrf2 水平升高的癌症。靶向 Nrf2 的抑制剂也有很多，比如 Brusatol 、ML385、 Luteolin 、Ochratoxin A、 Retinoic acid (ATRA)、 Trigonelline 等。 另外，据报道有几种机制可增强癌症中Nrf2 的活性，如 (1)体细胞的 KEAP1 、 CUL3 或 Nrf2 突变；(2) Keap1 的表观遗传沉默；(3) 破坏 Nrf2 和 Keap1 之间相互作用的蛋白质异常积累，如改变 Nrf2-Keap1 结合的 p21、p62；(4) 通过癌基因依赖性信号传导导致的 Nrf2 转录上调，如癌基因 K-Ras 通过 Mek-Erk-Jun 信号通路激活 Nrf2 转录；(5) 通过代谢中间体修饰 Keap1 等。 总而言之，Nrf2 的激活在癌症中作用是双重的。 为了预防氧化和炎症应激导致的慢性疾病和癌症，增强 Nrf2 的活性仍然是一种传统而有效的方法。但 Nrf2 在各种癌症中的组成性激活又会促进癌细胞增殖并导致癌细胞的化学抗性、放射抗性。因此，想知道 Nrf2 的激活是否会导致癌症，如何靶向 Nrf2 (直接或间接抑制上游蛋白激酶)，以及对 Keap1 结构进一步确定，还需要大家继续努力搞科研啦！                                                                         Nrf2 激活剂 Sulforaphane 可以激活 Nrf2，并通过 AMPK 依赖性信号传导抑制高糖诱导的胰腺癌。 Curcumin 乙酰转移酶 p300/CREB 结合蛋白特异性抑制剂；通过 Keap1 半胱氨酸修饰诱导 Nrf2 蛋白的稳定。 TBHQ 广泛使用的 Nrf2 激活剂，通过激活 Nrf2 来免受 Doxorubicin (DOX) 诱导的心脏毒性。 Resveratrol 天然多酚，具有抗氧化、抗炎、保护心脏和抗癌的特性。它的靶点广泛，例如 mTOR、JAK、β-amyloid、Adenylyl cyclase、IKKβ、DNA polymerase，也是 Nrf2 激活剂。 Oltipraz 一种 HIF-1α 激活抑制剂，也是强效的 Nrf2 激活剂。 Carnosol 一种有效的核糖体 S6 激酶 (RSK2) 抑制剂；Nrf2 激活剂，能提高细胞核内 Nrf2 的水平。                                                                                   Nrf2 抑制剂 Brusatol 可抑制 Nrf2，通过一种不依赖于 Keap1、蛋白酶体和自噬蛋白降解系统的机制激发 Nrf2 的消耗。 Luteolin 有效的 Nrf2 抑制剂，具有抗炎和抗癌特性。 Retinoic acid RAR 核受体的天然激动剂，对 RARα/β/γ 作用的IC50为 14 nM；可以通过激活视黄酸受体抑制 Nrf2。 Trigonelline 有潜在抗糖尿病活性的生物碱；有效的 Nrf2 抑制剂，能阻断 Nrf2 依赖性的蛋白酶体活性。 缩写： BTB domain: Broadcomplex/tramtrack/bric-a-brac domain IVR: Intervening region DGR domain: Double glycinerepeat domain参考文献 1. Tonelli C, et al. Transcriptional Regulation by Nrf2. Antioxid Redox Signal. 2018; 29(17): 1727-1745.2. Rojo de la Vega M, et al. NRF2 and the Hallmarks of Cancer. Cancer Cell. 2018; 34(1): 21-43. 3. Qin JJ, et al. Dual roles and therapeutic potential of Keap1-Nrf2 pathway in pancreatic cancer: a systematic review. Cell Commun Signal. 2019; 17(1): 121. 4. Zhang DD, et al. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex. Mol Cell Biol. 2004; 24(24): 10941-10953. 5. Canning P, et al. Structural basis of Keap1 interactions with Nrf2. Free Radic Biol Med. 2015; 88(Pt B): 101-107. 6. Jaramillo MC, et al. The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes Dev. 2013; 27(20): 2179-2191. 7. Taguchi K, et al. Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution. Genes Cells. 2011; 16(2): 123-140. 8. Zimta AA, et al. The Role of Nrf2 Activity in Cancer Development and Progression. Cancers (Basel). 2019; 11(11): 1755. 9. Wu S, et al. Nrf2 in cancers: A double-edged sword. Cancer Med. 2019; 8(5): 2252-2267. 10. Dodson M, et al. Non-canonical activation of NRF2: New insights and its relevance to disease. Curr Pathobiol Rep. 2017; 5(2): 171-176. 11. Silva-Islas CA, et al. Canonical and non-canonical mechanisms of Nrf2 activation. Pharmacol Res. 2018; 134: 92-99. 12. Katsuragi Y, et al. p62/SQSTM1 functions as a signaling hub and an autophagy adaptor. FEBS J. 2015; 282(24): 4672-4678. 13. Robledinos-Antón N, et al. Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development. Oxid Med Cell Longev. 2019; 2019: 9372182. 14. Menegon S, et al. The Dual Roles of NRF2 in Cancer. Trends Mol Med. 2016; 22(7): 578-593. 15. Wu S, et al. Nrf2 in cancers: A double-edged sword. Cancer Med. 2019; 8(5): 2252-2267. 16. Jiang T, et al. p62 links autophagy and Nrf2 signaling. Free Radic Biol Med. 2015; 88(Pt B): 199-204.

北京是280-420

damage指“损毁”，一般用于描述重大灾害后情况，较多用被动语态，eg.The building was damaged after the serious earthquake.【补充一个，ruin，指全面毁坏，成为废墟】destroy是指“（一般的）损坏”。 harm一般指心灵上的伤害、受伤。hurt一般指身体上受伤，挨揍了之类的…pain指“疼痛”，是挨揍的结果…injure指“受伤，负伤”，没有很特殊的语境，应该都行。wound是指“（战争中）负伤”。-ache一般是名词后缀，像headache(头疼)。

可以

schedule : 既可指时间或计划的安排表，又可指详细列出的所有分类项的清单或细表。calendar：只是指日历日，没有计划或安排的含义。

是这样的,calendar 多用于衡量时间,即日历这个意思比较常用,schedule 多用于安排时间.非要用calendar 的动词表示安排时间也是可以的,不过就不如schedule 表意明确和正式.

orchestra [ "ɔ:kistrə, -kes- ] . . n. 管弦乐队 band . . n. 带子,队,乐队 v. 联合,结合

schedule ----------------------------------- n.1. 时间表, 日程安排表2. 清单, 明细表3. （电视或广播）节目表4. （价格、收费或条款等的）一览表；明细表；清单5. 表格；报表6. [美国英语]预订日期；预定计划7. [美国英语]计划表，进度表 8. 课程表，课目表9. 火车时刻表10. (美国劳工部认为全国)人员短缺职业一览表(便于签发移民许可证)agenda --------------------------------------------n.1. 议事日程，（会议的）议程表2. 待议诸事项(一览表)，议事单，记事册3. 日常工作事项4. 目的；动机calendarn------------------------------.1. 日历, 月历2. 日程表3. （一年之中的）重大事件（或重要日期）一览表 4. 历法

歌曲名:Snitches歌手:Master P专辑:Mp Da Last Donfeat. Akon, Eminem+ (Eminem) {Akon}{Convict}(Yeah, SHADY){Convict Music}(Guess who"s back)Still here, haters{Akon & Obie Trice, Yeah}Whatcha gonna do it with it, A?Whatcha gonna do?{Take em on back to the streets}I keep the 40 call on my sideSteppin with the mindstate of the mobsterSee a nigga pass byTuck your chain in cause he might rob yaGot glocks for sale, red tops for saleAnything you need, believe me, I"m gonna lace youJust don"t whatever you do, SnitchCause you will get hit, pray I don"t lace you, yeahIt"s risky, the bitch tend to rise out a niggaIt"s history, Snitch, who decided he"s a memberOnce he got pinched, coincided with lawSame homie say he lay it down for the boyBrought game squad around oursHow could it be? Been homies since Superman drawsOnly foniness never came to parHe had us, a true neighborhood actorHad his back with K"sNow we see through him like X-Ray"sCuffed in that Adam carNo matter, his loss, we at him, it"s warKnowing not to cross those resevoir dogsYou helped plant seeds just to be a vegetableWhen we invest in team, it"s to the death fo shoNo ex and oh"s, tex calicosAim at your chest niccaI keep the 40 cal on my sideAnything you need, believe me, I"m gon lace youWe started out as a crew, in one speak, it"s all honestPrivate conferences when we eat, Benihana"sRecondences when we peep enemies on usBeen on these corners, sellin like anything on usKnowing heaven has shown us being devil"s minorsThat ain"t got shit to do with the tea in ChinaWe gon keep the grind up til death come find usMeanwhile in them European whips reclined upIt"s an eye for an eye for the ridersWe ain"t trying to get locked up, we soul survivorsPo Pos is cowards, there"s no you, it"s oursWe vow this, mixing yayo with soda powderWho woulda known he would fold and cowerOnce the captain showed, he sold whole McDonaldsSo no exs and ohs, tex calicosNowadays, Sammy Da Bull"s got the game fullSo he move to a rural area to keep coolHe snitchin on a snitch now, there"s nothin to tellNowadays, your circles should be small as hellAin"t tryin to meet new faces, this don"t interest meEven if we bubble slow, we"ll get it eventuallyNo penitentary, there will be no climacyYou will meet the lowest snitch in given us a centuryThese cats is rats now, the streets need deconThat"s how they react now, weak when the heat"s on emStop snitchin, you asked for the life your livingThis act is not permitted, Nowhere on the map, It isForbidden to send a nigga to prison if you been in itAlong with em and then snitch and become hiddenSo it"s no exs and ohs, techs calicosYou rat bastardhttp://music.baidu.com/song/2648127

1.whichever无论哪个;无论哪些 2.whatever无论什么 3.wherever无论哪里 4.however无论怎么样 5.whenever无论什么时候

他的老师在哪？

不行

一般现在进行时，是主系表结构。

区别如下：1、ache特指人身体机能或器官上的病理疼痛ache一般指身体某个部位持续的隐痛，常构成复合词，如：headache头痛，toothache牙痛，stomachache胃痛2、suffering疼痛;痛苦;折磨;苦难;苦恼(因疾病、痛苦、悲伤等)受苦，受难，受折磨;遭受;蒙受;变差;变糟[U]疼痛；痛苦；折磨；苦难physicalormentalpainDeathfinallybroughtanendtohersuffering.死亡终于结束了她的痛苦。

是不是operate formly 正式运营

employees stock option scheme雇员股票期权方案

watched、watch 看 were、be 是 took、take 拿earned、earn 赚得swam、swim 游泳did、 do 做 played、 play 玩visited visit 访问

歌曲名:Whenever歌手:CherishWheneverWe were sittin" at the table.We were talkin" bout some thangs.Conversatin" on what"s been goin" on lately.He moved in a little further.Said baby come a little closer.There is something that I want you to know.And then he said.Whenever you wanna get down.I"ll be around."Cause I"m in no hurry.Again he said.Whenever you fellin" the mood to let me love you.I"ll be here for youI put my hair behind my ear.Thinking if what I heard was clear.Turned my head thinking "bout what I should say.Then he said before you speak.You"re the only one for me.Baby I"m here for you whenever your ready.All while he speaks.Thoughts start to creep.I start to think.About the things.In time we could do.And then he said.Whenever you wanna get down.I"ll be around."Cause I"m in no hurry.Again he said.Whenever you fellin" the mood to let me love you.I"ll be here for youWhenever the time whenever the place.Baby just call or hit me on my two way.Baby I"m down for whatever you say.It"s all for you.And then he said.Whenever you wanna get down.I"ll be around."Cause I"m in no hurry.Whenever you fellin" the mood to let me love you.I"ll be here for youWhenever you wanna get down.I"ll be around."Cause I"m in no hurry.Whenever you fellin" the mood to let me love you.I"ll be here for youhttp://music.baidu.com/song/3492032

whatever，whoever，whichever，whenever，wherever, however用法归纳 一、引导状语从句它们都可用来引导状语从句(让步状语从句)，其大意为“无论什么(是谁、哪一个、什么时候、什么地方、如何)”等，相当于英语中的 no matter what (who, which, when, where, how)。如：Whatever [No matter what] you say, I believe you. 无论你说什么，我都相信你。Whoever [No matter who] telephones, tell them I"m out. 不管是谁打电话，都说我出去了。Whichever [No matter which] day you come, I"ll be pleasedto see you. 无论你哪天来，我都欢迎。Whenever [No matter when] you come, you are welcome. 你什么时候来，我们都欢迎。We found the people friendly wherever [no matter where] we went. 无论我们走到哪里，我们都发现人们很友好。However [No matter how] much he eats, he never gets fat. 无论他吃多少，他都不发胖。注：有时从句谓语可用情态动词：无论他在哪里，我都要找到他。正：I"ll find him, wherever he is.正：I"ll find him, wherever he may be.无论发生什么事都要保持冷静。正：Keep calm, whatever happens.正：Keep calm, whatever may happen另外，whoever 的宾格也是 whoever, 而不是 whomever, 后者在现代英语已基本不用，有的词典已不收录此词。如：Whoever you marry, make sure he can cook. 不管你跟谁结婚，他一定要会做饭才行。二、引导名词性从句除引导状语从句外，whatever, whoever, whichever等还可引导名词性从句(主语从句或宾语从句)。如：He does whatever she asks him to do. 她要他做什么，他就做什么。I will just say whatever comes into my mind. 我想到什么就说什么。Whoever breaks the rules will be punished. 谁违反这些规则都将受到处罚。I"ll give the ticket to whoever wants it. 请想要这票，我就把它给谁。Whichever team gains the most points wins. 哪个队得分最多，哪个队就赢。Whichever of us gets home first starts cooking. 我们当中无论哪个先到家，哪个就先开始做饭。三、用于加强语气有时用于加强语气，含有“究竟”、“到底”之义。如：Whatever [What ever] do you mean? 你到底是什么意思?Whenever [When ever] did you find time to do it? 你什么时候有空做这事?Wherever [Where ever] can the children be? 孩子们究竟会在哪里呢?Whoever [Who ever] told you that? 到底是谁告诉你的呢?Whichever [Which ever] did you choose? 你到底选了哪个?However [How ever] did you escape? 你到底是怎样逃出来的?“ No matter+ 疑问词”与“疑问词＋ ever ”用法透析1. “ No matter ＋疑问词”意为“无论……”、“不论……”，用来引导让步状语从句。如： no matter who / whom （无论谁）， no matter what （无论什么）， no matter which （无论哪一个）， no matter how （无论怎样）等。如：You are always welcome no matter where you are.无论在何地，您总是会受到欢迎的。No matter what may happen, they"ve decided to leave this evening.不管发生什么事，他们已决定今晚离开。No matter who you may be, you have no right to do such a thing.不论你是谁，你都无权做这样的事。No matter when my motherland needs me, I will go without hesitation.无论什么时候，只要祖国需要我，我都会毫不犹豫地出发。No matter how hard it may be, I will carry it out.无论此事有多难，我都会去做。2. “疑问词＋ ever ”相当于“ no matter + 疑问词”， ever 本是一个加强语气的词，加在疑问词后面作后缀，不仅使疑问词的语气加强，而且变为具有让步意义的一个复合词，可用于引导让步状语从句。例如：Whoever （ No matter who ） breaks the law, he should be punished.无论谁违反法律，都应该受到惩罚。Whatever you do, you must do it well.不管做什么事，你都要做好。Whatever problem you have, turn to me.不管你有什么问题，都可以找我帮忙。She is willing to help you, however busy she is.无论多忙，她都愿意帮助你。Wherever he is, he will be thinking of you.无论在哪儿，他都会想着你。3. 虽然“ no matter ＋疑问词”和“疑问词＋ ever ”都可以用来引导让步状语从句，但后者的用途更广，这类词（ whoever, whatever, whichever, whenever, wherever 等）还可用来引导主语从句、宾语从句、时间或地点状语从句等。例如：Whoever comes to the party will receive a gift.（主语从句）来参加晚会的人都会收到一份礼物。比较： Whoever comes to the party, he will receive a gift. （让步状语从句）＝ No matter who comes to the party, he will receive a gift.无论谁来参加晚会，都会收到一份礼物。You can take whichever book you like best. （宾语从句）你可以拿走你喜欢的任何一本书。Whenever we see him, we speak to him. （时间状语从句）每当我们见到他时，我们都跟他说话。一、注意从句的时态由no matter what/who/where/when…引导的从句往往用一般现在时或一般过去时。如：No matter who you are, you must obey the rules. 无论你是谁，都应该遵守规则。二、注意被修饰的名词、形容词以及副词的位置no matter what/whose/which修饰名词时，该名词必须紧跟其后；no matter how修饰形容词或副词时，该形容词或副词也必须紧跟其后。如：No matter how hard he works, he find it difficult to make ends meet. 无论他多么努力工作，却总是入不敷出。三、注意“no matter+疑问词”结构与“疑问词+ever”在用法上的区别1. “no matter+疑问词”结构只能引导让步状语从句，这时可以和“疑问词+ever”互换。如：No matter where he may be （=Wherever he may be）, he will be happy. 他无论在什么地方都快乐。2. 而“疑问词+ever”还可以引导名词性从句。如：Give this book to whoever likes it. 谁喜欢这本书就给谁吧。（这里不能用no matter who。）3. whoever既可引导名词性从句，又有在从句中作主语、宾语、表语等；whomever也可引导名词性从句，但只能在从句中作宾语。如：You may invite whomever you like.4. whatever表示“无论什么”，没有一定的范围限制；whichever表示“无论哪一个、无论哪些”，其后可接一个名词。如：Eat whichever cake you like.巩固练习：1. team wins on Saturday will go through to the national championships.A. No matter what B. No matter whichC. Whatever D. Whichever2. we gave him something to eat, he would save it up for his little sister.A. Whatever B. However C. Whenever D. Whichever3. Doctor Godwin says that what forceful arguments against cigarettes there are, many people insist on smoking.A. though B. however C. no matter D. even if4. In peace, too, the Red Gross is expected to send help there is human suffering.A. whoever B. however C. whatever D. wherever5. , Mother will wait for him to have dinner together.A. However late is he B. However he is lateC. However is he late D. However late he is6. Could you do me a favor?It depends on it is.A. which B. whichever C. what D. whatever7. The old tower must be saved, the cost.A. however B. whatever C. whichever D. wherever8. Sarah hopes to become a friend of shares her interests.A. anyone B. whomever C. whoever D. no matter who9. You can eat food free in my restaurant you like.A. whenever B. wherever C. whatever D. however10. much advice I gave him, he did exactly what he wanted to do.A. How B. Whatever C. However D. What参考答案：1~5 DCCDD 6~10 CBCAChowever用法详解一、考点描述however是高考英语中一个十分重要的考点，近几年来每年的各省考题均有所涉及。请看两道典型高考真题：1. You should try to get a good night"s sleep _____ much work you have to do.A. however B. no matter C. although D. whatever【分析】答案选A。however作连接副词时，与no matter how相当，后接形容词或副词，意为“无论……”“不管……”。句意是：不管你有多少工作要做，你都应该好好休息一个晚上。2. He tried his best to solve the problem, _____ difficult it was.A. however B. no matter C. whatever D. although【分析】答案选A。因difficult是形容词，修饰形容词要用连接副词however(无论如何，不管多么)，引导一个让步状语从句。二、用法详解不管however以何种形式出现在高考题中，它都不外乎以下两种用法。1. 用作副词(1) 表示让步：意为“无论如何”“不管怎样”，用来修饰形容词或副词，其词序为：however+形容词或副词+主语+谓语。这样用的however其实具有连词的功能，用以引导让步状语从句。如：Phone me when you arrive, however late it is. 你到达之后就给我打电话，不论多么晚也要打。however much he eats, he never gets fat. 不管他吃多少，他永远吃不胖。however cold it is, he always goes swimming. 不管天有多冷，他都去游泳。You won"t move the stone, however strong you are. 不管你力气有多大，也休想搬动那块石头。however far it is, l intend to drive there tonight 不管有多远，我今晚也要开车到那儿去。用于此用法时，请注意以下几点：①此用法属however所有用法中最重要的考点，同学们务请引起高度重视。②这样用的 however与 no matter how 大致同义。如：People always want more, however [no matter how] rich they are. 人总是富了还想再富。however [No matter how] hard I worked, she was never satisfied. 无论我多么努力地工作，她从来没满意过。③有时从句谓语可用情态动词。如：Don"t laugh, however funny it may be. 无论多么有趣也不要笑。I"ll try to finish it in time, however hard it may be. 无论多么难，我也要按时完成。④“however＋形容词或副词＋主语＋谓语”有时可以有所省略。如：I refuse, however favorable the conditions. 不管条件如何有利，我都不干。(conditions后省去了are)I"d rather have a room of my own, however small (it is), than share a room. 无论房间多么小，我宁愿一个人住一间，而不愿意与别人合住一个房间。A grammar rule, however true (it is), is useless unless it can be understood. 一条语法规则，不管如何正确，除非能懂，否则毫无用处。(2) 表示转折：尤其用于谈及一个既成事实时，表示转折，其意为“可是”“仍然”等。可放在句首、句中或句末，通常用逗号与句子其他成分隔开。如：My father, however, did not agree. 但是，我父亲不同意。My room is small; however, it"s comfortable. 我的房间很小，但却很舒服。He said that it was so; he was mistaken, however. 他说情况如此，可是他错了。注：however不能像 but(但是)那样直接连接两个句子(注意正句中的标点符号)。如：我们都已尽了最大的努力，不过我们还是输了。误：We all tried our best, however we lost the game.正：We all tried our best, but we lost the game.正：We all tried our best; however, we lost the game.正：We all tried our best. however, we lost the game.(3) 表示惊奇或强调：相当于how ever的用法，其意为“究竟怎样，到底以什么方式”。如：however did you get here without a car? 没有汽车你究竟是怎样来的呢?however does he manage to write music when he is so deaf? 他聋成这个样子，究竟是怎样从事作曲的呢?2. 用作连词用作连词，引导方式状语从句，表示“无论以何种方式”“不管怎样”。如：however it may be, I shall take your word. 无论如何，我将会相信你的话。however I approached the problem, I couldn"t find a solution. 这一问题我不管怎样都无法解决。however you travel, it"ll take you at least two days. 无论你怎么个走法，至少要两天时间。The painting looks wrong however you look at it. 这张画不论怎么看都显得不对劲。三、命题切入点高考以however切入命题的可能性主要有两个方面：1. 直接考查however的用法。如考查其句型结构(尤其是词序)，考查它与其他相似词语whatever, whenever, wherever, whichever, whoever等在用法和意义上的区别。如：(1) _____ rich one may be there is always something one wants.A. whatever B. Whenever C. however D. Wherever【分析】答案选C。however 用于修饰形容词rich，在意义上相当于no matter how。(2) We should report any incident, _____.A. however serious or minor it is B. how serious or minor is itC. it is how serious or minor D. it is however serious or minor【分析】答案选A。however 引导让步状语从句时的语序为“however+形容词或副词+主语+谓语”。(3) _____ I say, he always disagrees.A. however B. whatever C. Whichever D. Whoever【分析】答案选B。whatever 在此用作动词say的宾语，在意义上相当于 no matter what。(4) _____ she goes, there are crowds of people waiting to see her.A. Wherever B. however C. Whichever D. Whoever【分析】答案选A。根据句意可知，说话者强调的是地点，故用wherever。2. 用however作为干扰项进行考查。如：An awful accident _____, however occur the other day.A. does B. did C. has to D. had to【分析】此题正确答案应选B，句末的 the other day 意为“前几天”，所以句子应用过去时态，而选项D不合题意，故选B。此句有两个难点：一是句中插有 however 一词，分散了同学们的注意力；二是所填选项B为许多同学所不熟悉的强调用法。 whatever, whoever, whichever引导名词性从句1. whatever引导的名词性从句Whatever的意思是“所…的一切事或东西”，可视为what的强调说法，其含义大致相当于anything that，whatever在从句中可用作主语、宾语、定语：Whatever he did was right.无论他做什么都是对的。Give them whatever they desire.他们想要什么就给他们什么。I will just say whatever comes into my mind.我想到什么就说什么。Goats eat whatever (food) they can find.山羊找到什么(食物)就吃什么(食物)。I"m going to learn whatever my tutor wishes.我将学习任何我的导师愿意我学的东西。He does whatever she asks him to do.她要他做什么，他就做什么。Talk to me about whatever is troubling you.给我谈谈任何使你烦恼的事。One should stick to whatever one has begun.开始了的事就要坚持下去。She would tell him whatever news she got.她得到的任何消息都会告诉他。You can have whatever allowance you like.你想要多少津贴就给你多少津贴。

《The Abstinence Teacher》（Perrotta, Tom）电子书网盘下载免费在线阅读资源链接：链接：https://pan.baidu.com/s/1f2devxoUkkoq9PsKQpKGIw 提取码：cb5p书名：The Abstinence Teacher作者：Perrotta, Tom出版年份：2008-1页数：336内容简介：A sharp, funny and beautifully observed satire about the disturbing influence of the Christian right from one of America"s most cherished authors. Ruth Ramsey went too far. She hadn"t noticed the changing climate. A Sex Ed teacher "championing" oral sex!? Not now, not in this America! Cherished by her high school pupils as someone who"d tell it straight, after one innocent classroom indiscretion Ruth suddenly finds the curriculum she has taught for nigh on 15 years worryingly out of vogue. It seems these days the kids no longer need teaching; they need telling. As the scandal flares up and attracts the unwelcome eye of the local evangelical Church, the appeasing high-school principal forces her into advocating a pro-abstinence agenda in the classroom that is at odds with all conventional wisdom. Jaded though she is by her recent divorce and fruitless search for a new love, she is not yet ready to kneel at the altar of sophistry -- if common sense is to be sacrificed to Puritanism, she won"t let it pass without a fight. On the other hand, it is a syllabus change which Tim Mason, recovering addict, local football coach and recent convert to the same plaintiff Church, should consider a victory. But his new found faith is constantly put to the test by the temptations of his former wayward life, forcing him into grand, defensive statements of purpose. When he makes the gesture of leading his football team in prayer after a hard-fought victory, in which Ruth"s daughter Maggie starred, he manages not only to incur the wrathful attention of her mother, but to cement his position as the star evangelist of his church -- an office he is none too sure about occupying. "The Abstinence Teacher" is a cutting portrayal of modern America and the influence of the Christian right from the acclaimed, bestselling author of "Election" and "Little Children". Scathing, witty and brilliantly observed, it will doubtless confirm Perrotta"s standing as one of the finest chroniclers of American life.

The Abstinence Teacher链接：https://pan.baidu.com/s/1GSgEsqPuJP78nWWXjynvGA 提取码：LJNX

closet/wardrobe 口语中最常用的 五斗橱=dresser

kitchen cabinetn. 政府首脑的参谋团；厨房的餐具柜网络释义专业释义英英释义厨房内阁所谓“厨房内阁”（Kitchen Cabinet）是指总统本人有一个小小的顾问圈，这些顾问是总统的耳朵、眼睛和嘴巴，为总统收集信息、传递情报、出谋划策和试探政策。餐具柜橱柜厨房绸短语Perfect Kitchen & Cabinet 设计师演绎Kitchen and Cabinet China 中国国际橱柜展览会Kitchen n cabinet 餐具柜 ; 厨房橱柜21世纪大英汉词典 柯林斯英汉双解大词典 kitchen cabinet橱柜，碗柜[常作 K-C-Ja]厨房内阁(美国第七任总统杰克逊的私人顾问团)(政府首脑的)私人顾问团(或智囊团)Kitchen Cabinet(美国第七任总统杰克逊的)私人顾问团，厨房内阁以上来源于：《21世纪大英汉词典》双语例句权威例句Shape in interior design depends on the function of the object like a kitchen cabinet door. 室内设计中的平面图取决于对象的功能，比如设计一个橱柜门。article.yeeyan.orgOnce you have your bags you will find that most fold neatly and easily in your closet or akitchen cabinet. 一旦你有了自己的袋子，你会发现它们大多能方便整齐地叠放在你的衣柜或厨柜里。www.ebigear.comIt was the largest room in the apartment, and contained a stove and sink, a tub and a boiler, a table, two chairs, a kitchen cabinet, a wardrobe, and a couch with a red velvet spread thrown over it. 这是这栋公寓里最为宽敞一间，里面摆放着炉子，洗碗池，带热水器的浴缸，一张桌子，两条凳子，一个碗橱，一个衣橱，一张套着红色羽绒面的沙发。

国会，内阁，乐团

1.美国立法者在国会达成初步协议于周日在一项价值7000亿元的纾困计划以购买不良贷款的金融机构没有受到贷款。2.民主党人说,他们正在考虑一项提议建立金融机构如果纳税人费用从政府失去了金钱购置资产3.美国。总统乔治·w·布什在星期三敦促国会批准7000亿-dollarbailout计划,说一个失败可能导致美国成“一个长期而痛苦的衰退。”

不对，多了by，这是一个倒装句，the teacher是主语，said是谓语，前面的引号里的话是宾语，不需要介词。

英音 [ "æŋkə ] ； 美音 [ "æŋkə ] 可数名词：1. 可以依靠的人或事物，靠山，后盾2. 锚，锚固装置（用缆﹑链等连接着的金属设备，用以将船舶固定于海底或将气球固定在地面上）3.[=anchorman, anchorwoman]【美】（尤指无线电或电视采访的）主持人动词：抛锚，用锚固装置固定（某物）词形变化：名词：anchorage；时态：anchored，anchoring，anchors。同义词：drop anchor，cast anchor；ground；ground tackle；keystone，backbone，linchpin，lynchpin，mainstay；manperson。

这个还有问的，我英语四级都没有过

歌曲名:Flowers歌手:The Psychedelic Furs专辑:Original Album ClassicsNikki Flores - FlowersI"m complicatedMy colors are shadedMaking me strongBut sometimes I"ve fadedI can"t be perfectNot even close tooI let my guard downAnd baby I know youPush me too hardIt"s more than I can takeI"m fragile I can break like flowersDon"t tear us apartIt took so long to growDon"t let the petals fall like flowersFlowers flowers flowersI was so openIm starting to closeDefending my heartLike a thorn on a roseDon"t let it dwindleDown into nothingBring back the man I fell in love withYou push me too hardIt"s more than I can takeI"m fragile I can break like flowersDon"t tear us apartIt took so long to growDon"t let the petals fall like flowersFlowers flowers flowersFlowers need the sunFlowers need the rainBut they don"t need someoneThey don"t feel the painLike I do, I doI need youDon"t let it dwindleDown into nothingBring back the man I fell in love withYou push me too hardDon"t tear us apartFlowersLike flowershttp://music.baidu.com/song/7519014

A in advance of 固定搭配，提前。他把车开得飞快,比预定时间提前1个钟到达。

四个女人，走两头并进的临近，他们的鞋子的木制走道上大声

“petrol&chemical”的意思是“石油化工”。